نتایج جستجو برای: acute thrombocytopenia

تعداد نتایج: 516851  

Journal: :Blood 2012
Iléana Antony-Debré Dominique Bluteau Raphael Itzykson Véronique Baccini Aline Renneville Françoise Boehlen Margot Morabito Nathalie Droin Caroline Deswarte Yunhua Chang Guy Leverger Eric Solary William Vainchenker Rémi Favier Hana Raslova

RUNX1 gene alterations are associated with acquired and inherited hematologic malignancies that include familial platelet disorder/acute myeloid leukemia, primary or secondary acute myeloid leukemia, and chronic myelomonocytic leukemia. Recently, we reported that RUNX1-mediated silencing of nonmuscle myosin heavy chain IIB (MYH10) was required for megakaryocyte ploidization and maturation. Here...

2011
Carlos Chagas Djalma Batista

Malaria affects almost all blood components and is a true haematological infectious disease. Anaemia and thrombocytopenia are the most frequent malaria-associated haematological complications (Wickramasinghe & Abdalla 2000) and have received more attention in the scientific literature due to their associated mortality. On the other hand, thrombocytopenia is less studied, causes negligible morta...

2008
Yan Liu Xangshan Chao Weiying Gu Xiaoying Hua Ning Xu

It is well known that acute leukemia may accompany thromboembolic events; even severe thrombocytopenia does not prevent thrombosis. Coagulation dysfunction is the major pathophysiological background for thromboembolism in these patients. Most thromboembolism is localized in venous vessels in acute leukemic patients and it happens rarely in the artery. We report a case of acute thrombosis in the...

Journal: :Blood 1992
R J Hill M K Warren J Levin J Gauldie

The induction of thrombocytopenia results in elevated levels of thrombopoietin (TPO), which can be detected in the plasma of experimental animals. Acute, severe thrombocytopenia (platelet count less than 5% of control) was produced in mice by the administration of either guinea pig or rabbit antimouse platelet antiserum. Control mice received equal volumes of normal serum. At various times afte...

Journal: :Baylor University Medical Center Proceedings 2012

Journal: :Indian Journal of Hematology and Blood Transfusion 2013

2017
Emma Birnie Gavin C. K. W. Koh Ester C. Löwenberg Joost C. M. Meijers Rapeephan R. Maude Nicholas P. J. Day Sharon J. Peacock Tom van der Poll W. Joost Wiersinga

BACKGROUND Melioidosis, caused by bioterror treat agent Burkholderia pseudomallei, is an important cause of community-acquired Gram-negative sepsis in Southeast Asia and Northern Australia. New insights into the pathogenesis of melioidosis may help improve treatment and decrease mortality rates from this dreadful disease. We hypothesized that changes in Von Willebrand factor (VWF) function shou...

Journal: :International Journal of Health Sciences (IJHS) 2022

Introduction: Many viral and bacterial infections result in thrombocytopenia are most common non-iatrogenic cause of thrombocytopenia. Infections can affect both platelet production survival. In addition, immune mechanisms also be a cause, as immune-mediated (ITP) children following infection. our setup, tropical like malaria, dengue leptospirosis formed the important causes Objectives: To corr...

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