We review the clinical courses and outcomes of an outbreak of enteroviral infection that occurred in 5 children with acute lymphoblastic leukemia during a 2-month period in a hematology-oncology unit. Three patients presented with encephalitis and 2 with parotitis. Three of the 5 patients recovered uneventfully and 2 died, 1 of chronic encephalitis and 1 of acute brain stem encephalitis.

Acute viral encephalitis caused by neurotrophic viruses, such as mosquito-borne flaviviruses, is an emerging and re-emerging disease that represents an immense global health problem. Considerable progression has been made in understanding the pathogenesis of acute viral encephalitis, but the immune-pathological processes occurring during the progression of encephalitis and the roles played by v...

Results We report a case of an infant, 1 year and 8 months old, male, that was in intensive care unit for five months with initial diagnosis of acute diarrhea, dehydration and hemolytic uremic syndrome. The infant developed fever, hepatosplenomegaly, cutaneous rash, bicytopenia, elevated serum ferritin, liver enzyme abnormalities, encephalitis, acute renal failure and serum hypogammaglobulinemi...

BACKGROUND Herpes simplex virus (HSV) encephalitis is a life-threatening infection of the brain, which has significant physical, cognitive and social consequences for survivors. Despite increasing recognition of the long-term effects of encephalitis, research and policy remains largely focused on its acute management, meaning there is little understanding of the difficulties people face after d...

Bickerstaff Brainstem Encephalitis (BBE) is a post-infectious immune disorder. It is rare, yet the most severe variant of Guillain-Barre Syndrome (GBS) in terms of initial presentation. Moreover, the coexistence of BBE and Acute Lymphoblastic Leukaemia (ALL) is distinctly uncommon. We report a case of a patient with a background history of Precursor B cell Acute Lymphoblastic Leukaemia (pre B A...