We describe three cases of acute disseminated encephalomyelitis (an immune-mediated inflammatory demyelinating disease of the central nervous system) and their histology, showing different radiological features. One appearance is a few ring-shaped enhancing lesions, which are found predominantly in the supratentorial white matter, the other is solid disseminated lesions.

IMPORTANCE Classically, transverse myelitis and acute disseminated encephalomyelitis are considered central nervous system demyelinating conditions. In both conditions, the spinal cord is involved to varying degrees, and there is a variety of presentations, usually involving some degree of progressive paralysis of the upper and/or lower extremities. Treatment usually consists of high-dose intra...

Many of the central and peripheral nervous system complications related to severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection have been recently described. An efficient mass vaccination program is required in order effectively reduce spreading and, therefore, minimize long-term sequelae, including neurological ones. Nonetheless, as more patients are accessing 2019 (COVID-19) v...