نتایج جستجو برای: acute and chronic toxicity

تعداد نتایج: 17050953  

ژورنال: پزشکی قانونی 2019
Aghabiklooei, A., Amiri, H., Neghabi, Z.,

Aims): Lead is one of the heavy metals that can be a factor of acute or chronic toxicity. Smugglers may add lead to drugs during the production process in order to increase its weight and earning more benefits. In this regard, the aim of the present study was to investigate the relationship between blood lead levels in consumers of edible opium with abdominal pain. Instruments & Methods: This ...

2016
Martin May Wiebke Drost Sabine Germer Tanja Juffernholz Stefan Hahn

BACKGROUND Acute-to-chronic extrapolation is an important approach to predict acceptable no-effect levels from acute data which has some uncertainties, but is valuable for risk assessment of chemical substances. With regard to the still limited and heterogenic data of chronic fish tests, conclusions on aquatic hazard estimation need to be checked and the question arises whether the chronic toxi...

Journal: :Chemosphere 2011
José-Manuel Zaldívar Joaquín Baraibar

There is the need to integrate existing toxicity data in a coherent framework for extending their domain of applicability as well as their extrapolation potential. This integration would also reduce time and cost-consuming aspects of these tests and reduce animal usage. In this work, based on data extracted from literature, we have assessed the advantages that a dynamic biology-toxicant fate co...

Journal: :Water science and technology : a journal of the International Association on Water Pollution Research 2013
Alessandra Cunha Lopes Ann H Mounteer Teynha Valverde Stoppa Davi Santiago Aquino

Eucalyptus bleached kraft pulp production, an important sector of the Brazilian national economy, is responsible for generating large volume, high pollutant load effluents, containing a considerable fraction of recalcitrant organic matter. The objectives of this study were to quantify the biological activity of the effluent from a eucalyptus bleached kraft pulp mill, characterize the nature of ...

1993
G. T. Ankley M. K. Schubauer

In 1989, the guidance document for acutely toxic effluents entitled Methods for Aquatic Toxicity Identification Evaluations: Phase Ill Toxicity Confirmation Procedures was published (EPA, 19890). This new Phase Ill manual and its companion documents (EPA, 1991 A; EPA, 1992; EPA, 1993A) are intended to provide guidance to aid dischargers in confirming the cause of toxicity in industrial and muni...

Journal: :iranian journal of pharmaceutical sciences 0
seyed nasser ostad department of toxicology and pharmacology, faculty of pharmacy, tehran university of medical sciences, tehran, iran, manochehr hamedi department of food industry, karaj agriculture university, karaj, iran hamidreza monsef esfahani department of pharmacognosy, faculty of pharmacy, tehran university of medical sciences, tehran, iran, seyed mohammad shariatpanahi department of toxicology and pharmacology, faculty of pharmacy, tehran university of medical sciences, azizi ebrahim department of toxicology and pharmacology, faculty of pharmacy, tehran university of medical sciences, tehran, iran, mohammad seyedabadi department of pharmacology, school of medicine faculty of pharmacy, tehran university of medical sciences, tehran, iran, mehran mohseni

toxic and direct teratogenic potential of two dominant iranian cultivars of carthamus tinctorius (safflower), floret extracts, il 111 and lrv 51 51, were investigated. the extracts are commonly used in foods and medicinal products. neither death nor alteration of stereotype activities was observed with il 111 and lrv 51 51 extracts up to 17 g/kg in 48 h in mice and rats. haemoglobin was decreas...

2008
Tales Alexandre Aversi-Ferreira Guilherme Nobre

Objectives: to compare the acute and chronic effects of ethanol on the neural development, by analysis of the ontogenetic neural structure of mammals. Methods: searches were performed in the following electronic databases: MEDLINE, SciElo, PubMed, LILACS, CAPES periodical, and the Open Journal System. The descriptors used were: "chronic ethanol toxicity", "chronic alcohol toxicity", "acute etha...

2016
Kokou Idoh Amegnona Agbonon Yao Potchoo Messanvi Gbeassor

INTRODUCTION Clerodendrum capitatum (Willd) Schumach. & Thonn (Lamiaceae) is used in African traditional medicine for the treatment of malaria, hypertension, obesity, jaundice and diabetes however there is lack of experimental data on its possible toxicity. This study investigated the acute and 28 days sub-chronic toxicity of C. capitatum in Wistar rats. METHODS In acute toxicity tests, a sin...

Background: Brucella is a well-known intracellular bacterium entailing acute and chronic illnesses in humans and domestic animals. The infection chronicity may be affected by the cell-mediated immunity and cytokine patterns. Objective: To evaluate the patterns of T-helper cytokines in patients suffering from chronic and acute brucellosis. Methods: In this cross-sectional study, 22 individuals w...

Alireza Esmaeili Bita Dadpour, Fatemeh Hoseini Shahrad Tajoddini

Background: Arsenic toxicity as a result of consumption of hair removal agent has been rarely seen in last few years in comparison with the past. Case Presentation: In this case report, we presented a middle age woman referred to medical toxicology department due to epigastric pain and diarrhea following ingestion of hair removal agent. Urinary test for arsenic was positive. ECG changes and ele...

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