The influential roles of antibiotic prophylaxis on cirrhotic patients with peptic ulcer bleeding are still not well documented. The purpose of this study is to clarify these influential roles and to identify the risk factors associated with rebleeding, bacterial infection and in-hospital mortality. A cross-sectional, chart review study was conducted on 210 cirrhotic patients with acute peptic u...

Helicobacter pylori (H. pylori) is causally related to chronic active gastritis, peptic ulcer disease, primary low-grade B-cell gastric lymphoma, and is also a risk factor for gastric cancer. In addition, a high seroprevalence of H. pylori has been found in many extragastrointestinal disorders, including active bronchiectasis and chronic obstructive pulmonary disease (COPD). It appears that H. ...

BACKGROUND Widely studied for the past 20 years, hepatocyte growth factor (HGF) has been identified as a regenerative marker and an important factor in the development and healing of injuries. Antithrombin III (AT III) is a protein in the blood stream with anti-thrombotic and anti-inflammatory properties and has been used as an adjuvant treatment along with antibiotics in severe sepsis. OBJEC...

aqueous (hydrophilic) and chloroform (lipophilic) extracts of nine medicinal plants currently used in traditional medicine, in egypt, to treat some gastrointestinal tract (git) disorders were tested for their gastro-protective effect against the incidence of peptic ulcer. indomethacin-induced ulcer in a rat model was used for this testing. mentha microphylla, brassica oleracea capitata (cabbage...

Inflammatory changes within varicose veins can result in skin complications including venous leg ulcer (VLU). We have previously proposed that cytokines involved T cell activation are markers of disease and may be targets to attenuate progression. Here, we measured circulating from subjects with without ulcer. hypothesized associated interferon gamma (IFN-γ), IL-2, IL-12p70 would elevated vein ...

BACKGROUND Helicobacter pylori (H. pylori) infection is known to be associated with a spectrum of gastroduodenal diseases. We studied the association of H. pylori virulence markers cytotoxin-associated gene (cagA) and vacuolating associated cytotoxin gene (vacA) alleles in patients with non ulcer dyspepsia (NUD), gastric ulcer (GU), gastric carcinoma (GC) and duodenal ulcer (DU). METHODS H. p...

In this study, target compounds 5-12 were synthesized via acid amine coupling of ibuprofen and naproxen with methyl ester derivatives of amino acids, namely, l-proline, sarcosine, l-tyrosine, and l-glutamic acid. When tested for anti-inflammatory activity using the acute carrageenan-induced hind paw method in rats, compounds 5-12 showed significantly greater anti-inflammatory activity, in the r...

OBJECTIVE To detect the presence of virulence markers cytotoxin-associated (cagA) and vacuolating cytotoxin-associated (vacA) genes in gastric biopsy specimens of patients with gastroduodenal disorders. METHODS This study was conducted at the Department of Pathology, King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia between March 2008 and February 2009. A total of 118 gastric b...

Objective: To investigate the anti ulcer effect of aqueous extract of Azolla filiculoides (AF) in experimentally induced gastric ulceration in male Wistar rats. Methods: Twenty four rats were divided into four groups of six rats in each group. The group I and III rats were fed with standard diet, whereas, group II and IV rats were pre-treated orally with aqueous extract of Azolla filiculoides (...