Multiple sclerosis (MS) is a complex neurological disease and its prevalence is about 2 million in the world. Neuroinflammation plays a key role in MS. Vitamins are essential nutrients that have effective role on immune system including activation of lymphocyte and differentiation of T-helper cell. Vitamin D is a micronutrient that is effective on immune function. Deficiently of Vitamin D is a ...

objective(s): so far, extensive research has been conducted on the preparation and characterization of nano ceramics based on ca-si by sol- gel method and bioactivity was evaluated, but, a few researches have paid attention to the preparation of materials by mechanical activation (ma). the aim of this study was the preparation of akermanite nano powder by mechanical activation method and bioact...

fertilization is triggered by changes in intracellular calcium concentration. in mammals, these transients in ooplasmic calcium concentration take the form of repetitive spikes, so called calcium oscillations (ca2+-oscillations). these oscillations are important for relieve of meiotic arrest and to induce all the other events of oocyte activation. although a surface mediated way of oocyte activ...

Background: Hypoactive sexual desire disorder is the most common sexual disorder among women, which interferes with their various functions. Activity of brain-behavioral and psychological distress systems are considered among factors affecting sexual function. Objectives: The present study aimed to compare women with hypoactive sexual desire and normal women in terms of brain-behavioral and ...

Repeated administration of morphine sensitizes animals to the stimulant and rewarding properties of the drug. It may also alter the expression and function of GABA receptors within the ventral tegmental area (VTA), a midbrain region that is implicated in morphine action. In the present study, the effect of activation of GABAB receptor subtypes within the VTA on morphine-induced incentive sensit...

Repeated administration of morphine sensitizes animals to the stimulant and rewarding properties of the drug. It may also alter the expression and function of GABA receptors within the ventral tegmental area (VTA), a midbrain region that is implicated in morphine action. In the present study, the effect of activation of GABAB receptor subtypes within the VTA on morphine-induced incentive sensit...

Abstract Activation functions play a vital role in the training of Convolutional Neural Networks. For this reason, developing efficient and well-performing is crucial problem deep learning community. The idea these approaches to allow reliable parameter learning, avoiding vanishing gradient problems. goal work propose an ensemble Networks trained using several different activation functions. Mo...

Background: Macrophages activation is the important anti-leishmania immune response. Different signals could affect macrophages development and functional activation. Objectives: In the present study, we compared the effect of Leishmania Soluble Antigen (LSA)and Lipopolysaccharide (LPS) on peritoneal macrophage responses. Appropriate activation of macrophages depends on thesignals they receive ...