Fluorination has been widely used in chemical synthesis, but is rare in nature. The only known biological fluorination scope is represented by the pathway fl from that produces fluoroacetate (FAc) and Streptomyces cattleya 4-fluorothreonine (4-FT). Here we report the identification of a novel pathway for FAc and 4-FT biosynthesis from the actinomycetoma-causing pathogen ATCC 700358. The new pat...
