نتایج جستجو برای: acridone

تعداد نتایج: 167  

Journal: :Biological & pharmaceutical bulletin 2004
Norihito Chaya Kazuko Terauchi Yuriko Yamagata Junei Kinjo Hikaru Okabe

The MeOH extracts of the ground part and the root of Boenninghausenia japonica NAKAI showed inhibitory activity against tumor cell growth. Fractionation of the extracts has resulted in isolation of 1,3-dihydroxy-4-(2'-hydroxy-3'-hydroxymethyl-3',4'-epoxy-butyl)-N-methylacridone, 1,3-dihydroxy-4-[(Z)-3'-hydroxy-3'-methyl-buten-1'-yl]-N-methylacridone, 3-(1',1'-dimethylallyl)-7-hydroxy-8-methoxy-...

Journal: :Revista Brasileira de Farmacognosia 2022

Abstract Citrus fruits are among the most important economical crops, because of their nutritional value, medicinal importance, and unique flavor. Gas liquid chromatography-mass spectrometry hydro-distilled oil from root resulted in identification 110 compounds with germacrene B (22%), aromadendrene (21.6%), α-santalene (7.1%), geijerene (4,81%), D (4.3%), limonene (3.4%) as major constituents....

Journal: :Molecular pharmacology 1997
J K Horton K N Thimmaiah G A Altenberg A F Castro G S Germain G K Gowda P J Houghton

Novel compounds, composed of two acridone moieties connected by a propyl or butyl spacer, were synthesized and tested as potential modulators of P-glycoprotein (P-gp)-mediated multidrug resistance. The propyl derivative 1,3-bis(9-oxoacridin-10-yl)-propane (PBA) was extremely potent and, at a concentration of 1 microM, increased steady state accumulation of vinblastine (VLB) approximately 9-fold...

2013
Ramasamy S. Annadurai Ramprasad Neethiraj Vasanthan Jayakumar Anand C. Damodaran Sudha Narayana Rao Mohan A. V. S. K. Katta Sreeja Gopinathan Santosh Prasad Sarma Vanitha Senthilkumar Vidya Niranjan Ashok Gopinath Raja C. Mugasimangalam

Herbal remedies are increasingly being recognised in recent years as alternative medicine for a number of diseases including cancer. Curcuma longa L., commonly known as turmeric is used as a culinary spice in India and in many Asian countries has been attributed to lower incidences of gastrointestinal cancers. Curcumin, a secondary metabolite isolated from the rhizomes of this plant has been sh...

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