INTRODUCTION Determination of microbial genetic relatedness is important for improving efficiency of infection control measures during hospital outbreaks. This study aimed to analyze the clonal relationships of clinical and environmental Acinetobacter baumannii strains isolated during an outbreak in the intensive care unit (ICU) of a secondary care hospital in Saudi Arabia. METHODOLOGY Twelve...

Abstract Introduction Identification of a causative agent in patients with infective endocarditis (IE) is crucial for diagnostic and prescribing etiotropic therapy which defines positive outcome disease. High rate culture negative IE inaccurate results traditional microbiological methods raise concern. So the etiological diagnostics are need development, particularly introduction polymerase cha...

We report herein the synthesis of a new biologically active 3,4-dihydropyrimidin-2(1H)-thione derivative (4) from 9-phenanthrenecarboxaldehyde, thiourea, and methyl acetoacetate by Biginelli reaction. The structure synthesized compound was investigated NMR spectroscopy, mass spectrometry, elemental analysis. Moreover, to gain insight into conformation crystal packing, novel dihydropyrimidine al...

To the Editor Carbapenems (i.e. ertapenem, imipenem, meropenem, and doripenem) are second line antimicrobials reserved to treat serious infections, including those caused by Gramnegative bacilli (GNB) producing extended-spectrum b-lactamses (ESBLs). ESBLs mediate resistance among GNB to b-lactam drugs, including third generation cephalosporins. Emergence of carbapenemases-producing GNB (mainly ...

Introduction. Nosocomial infections are a common complication in patients hospitalized intensive care units. The aims of this research were to examine the incidence nosocomial admitted pediatric surgical unit, impact hospital length stay and type disease on infections, frequency microorganisms causing their antibiotic susceptibility profile. Material Methods. Data 50 subjects extracted from dat...