A fundamental structural feature of benzimidazoles, a group heterocyclic, aromatic compounds, is the fusion six-membered benzene ring with five-membered imidazole moiety. Formic acid, Acetyl chloride, hydrazine hydrate, Benzene-1,2-diol, Glycolic Acid, Benzoyl Methyl Ethyl Benzamide, and other chemicals were utilized in this research study. In study different methods used such as TLC, IR spectr...

OBJECTIVES To examine possible modulators of the ion transport through the apical membrane of the nasal polyps. METHODS The study was conducted using the freshly-excised nasal polyps from the patients with chronic sinusitis. A voltage-sensitive vibrating probe technique was introduced to monitor the short-circuit current across the apical membrane of the polyp at 37°C. RESULTS In the presen...

Ten new synthetic thiazolidine-4-ones derivatives (5 chlorothiazolidine-4-ones, 3 methoxythiazolidine-4-ones and 2 hydoxythiazolidine-4-ones) having different substituents at R1, R2 and R3 were evaluated for their analgesic activity using different animal models and their structure activity relationship was also elucidated. Chlorothiazolidine-4-ones and methoxythiazolidine-4-ones exhibited anal...

A simple stereoselective synthesis of montroumarin [(3S)-6,8-dihydroxy-3-phenyl-3,4-dihydroisocoumarin] isolated from Montrouziera sphaeroidea has been achieved. Condensation of benzoyl chloride with 3,5-dimethoxyhomophthalic acid afforded 6,8-dimethoxy-3-phenylisocoumarin (3) which on sequential saponification and esterification yielded the keto ester 5. Enantioselective reduction of the latte...

In the title compound, C(16)H(11)NO(4)S, the nine-membered fused ring is nearly planar, with maximum deviations from the mean plane of -0.022 (1) Å for the N atom and 0.011 (1) Å for the S atom, and makes a dihedral angle of 53.56 (7)° with the phenyl ring. The crystal structure is stabilized by O-H⋯O and C-H⋯O hydrogen-bonding inter-actions.

Submit Manuscript | http://medcraveonline.com Abbreviations: GPC: Gel Permeation Chromatography; FTIR: Fourier Transform Infra Red; XRD: X Ray Diffraction; HRTEM: High Resolution Transmission Electron Microscopy; TGA: Thermo Gravimetric Analysis; IEC 60520: International Electronic Commission Number 60520; BS 7655: British Standard Number 7655; PMMA: Poly Methyl Methacrylate; PC: Poly Carbonate...

Background and Objectives: Zinc oxide (ZnO) nano-particles have been proven to have strong antibacterial activity against food borne pathogens. The practical applications of different concentrations (Control, 0, 1, 2, 4, 6 and 8 mM) of ZnO suspensions containing 1% acetic acid were investigated against the pathogenic bacteria like Staphylococcus aureus. Materials and Methods: The projects of l...