نتایج جستجو برای: acetaminophen poisoning

تعداد نتایج: 39034  

2015
Ilse Gradwohl-Matis Jakob Pann Christian A. Schmittinger Andreas Brunauer Daniel Dankl Martin W. Dünser

BACKGROUND Miosis occurs following exposure to toxins that decrease the sympathomimetic tone, increase the cholinergic tone, or exert sedative-hypnotic effects, but has not been reported in insulin poisoning. CASE REPORT A 64-year- old woman without co-morbidities was found unconscious next to an empty insulin pen. Her Glasgow Coma Scale was 3 with absent reflexes, bilateral reactive miosis, ...

Journal: :Alternative medicine review : a journal of clinical therapeutic 1998
G S Kelly

N-acetylcysteine (NAC), the acetylated variant of the amino acid L-cysteine, is an excellent source of sulfhydryl (SH) groups, and is converted in the body into metabolites capable of stimulating glutathione (GSH) synthesis, promoting detoxification, and acting directly as free radical scavengers. Administration of NAC has historically been as a mucolytic agent in a variety of respiratory illne...

Journal: :Gastroenterology research and practice 2015
Murat Polat Serkan Cerrah Bulent Albayrak Serkan Ipek Mahmut Arabul Fatih Aslan Omer Yilmaz

Background Aim. In case of high-dose acetaminophen intake, the active metabolite can not bind to the glutathione, thereby inducing cellular necrosis through binding to the cytosol proteins. This trial was performed to histologically and biochemically investigate whether leptin was protective against liver damage induced by paracetamol at toxic doses. Material and Method. In our trial, 30 female...

Journal: :Postgraduate medical journal 1980
M Helliwell

Charcoal haemoperfusion was successful in the treatment of severe butobarbitone poisoning complicated by resistant hypotension. At the same time the rapid removal of paracetamol may have lessened the severity of the subsequent hepatic injury. The mechanism and management of shock associated with barbiturate poisoning, and the possible application of haemoperfusion in paracetamol poisoning are d...

ژورنال: بیهوشی و درد 2022

Background: Pain relief after C/S is very important. Acetaminophen is one of the most common drugs to control post-operative pain. Due to the fact that Acetaminophen IV should be injected several times a day for patients, to save time, manpower and cost, it is recommended to inject intravenous Acetaminophen in 24-hour drip. Therefore, this study was designed and performed to compare Acetaminoph...

2015
Laura James Ke Yan Lisa Pence Pippa Simpson Sudeepa Bhattacharyya Pritmohinder Gill Lynda Letzig Gregory Kearns Richard Beger Gustavo Batista Menezes

Metabolomics approaches have enabled the study of new mechanisms of liver injury in experimental models of drug toxicity. Disruption of bile acid homeostasis is a known mechanism of drug induced liver injury. The relationship of individual bile acids to indicators of oxidative drug metabolism (acetaminophen protein adducts) and liver injury was examined in children with acetaminophen overdose, ...

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