Recent data underscore the importance of intertissue communication in the maintenance of normal glucose homeostasis. Important signals are conveyed by hormones, cytokines, and fuel substrates and are sensed through a variety of cellular mechanisms. The ability of tissues to sense and adapt to changes in metabolic status and fuel availability is altered in insulin-resistant states including type...

In this paper, a non-isothermal two-phase flow in the cathode gas diffusion layer (GDL) of PEM fuel cell is modeled. The governing equations including energy, mass and momentum conservation equations are solved by numerical methods. Also, the optimal values of the effective parameters such as the electrodes porosity, gas diffusion layer (GDL) thickness and inlet relative humidity are calculated...

in this paper, plug-in fuel cell electric vehicle (pfcev) is considered with dual power sources including fuel cell (fc) and battery energy storage. in order to respond to a transient power demand, usually supercapacitor energy storage device is combined with fuel cell to create a hybrid system with high energy density of fuel cell and the high power density of battery. in order to simulate the...

Pulsatile insulin output, paralleled by oscillations in intracellular Ca(2+), reflect oscillating metabolism within beta-cells in response to secretory fuels. Here we question whether oscillatory periodicity is conserved or varied from stimulation to stimulation, whether glycolysis is essential for the manifestation of an oscillatory response, and if an environment of nutrient oversupply affect...

Neurons are thought to primarily rely on glucose to fuel mitochondrial metabolism. In this issue, Divakaruni et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201612067) show that neurons are also happy to use glutamate. When neurons use this neurotransmitter, its concentration drops, thus protecting against glutamate-induced excitotoxic stress.

In this paper, Plug-in Fuel Cell Electric Vehicle (PFCEV) is considered with dual power sources including Fuel Cell (FC) and battery Energy Storage. In order to respond to a transient power demand, usually supercapacitor energy storage device is combined with fuel cell to create a hybrid system with high energy density of fuel cell and the high power density of battery. In order to simulate the...