The study of wound closure is important for the advancement of medicinal applications in surgical scar healing, as well as initiation of tissue regeneration. Research on wound closure has primarily focused on vertebrate models, although the process is found throughout all animal groups. Non-vertebrate models provide efficient cost-effective tools for examining the general properties necessary f...

Objective(s) The process of wound healing involves tightly integrated events including inflammation, granulation tissue formation and remodeling. Systemic administration of L-arginine promotes wound healing but its global side effects are undesirable. To confine the action of L-arginine at the site of injury, we tested the effects of local administration of L-arginine on the healing of excisio...

RESULTS: Following a normal, spontaneous vaginal delivery, the patient underwent bone grafts and ORIF of the left forearm and metacarpal bones. We then utilized the newly available and pliable abdominal skin to cover the large soft tissue defect. The abdominal wall flap was raised, thinned and then the injured extremity was carefully inset in a subcutaneous abdominal pocket and a meshed bilayer...

Burst abdomen and incisional herniation are continuing problems for the general surgeon. A prospective study was carried out to define the extent of the problem. Over five years from 1975 to 1980 a total of 1129 major laparotomy wounds in adults were assessed at regular intervals for 12 months after operation. There were 19 burst abdomens (1.7%) and 84 incisional hernias (7.4%). The introductio...

Open wound managment after perforated appendicitis has been a common practice but recently, primary closure has been advocated to reduce costs and morbidity. For comparing delayed closures against primary closure with vacuum drainage, a randomized experimental study was designed. in Kerman. Sixty patients with perforated appendicitis divided randomly in two groups and evaluated on day of discha...

OBJECTIVES To determine the current practice of abdominal fascial closure among provincial general surgeons. The primary objective was to determine the proportion of surgeons choosing absorbable versus nonabsorbable sutures. Secondary objectives included determining knowledge and attitudes of surgeons to evidence-based medicine and concordance of current practice with level I evidence. DESIGN...

This study examined the effect of monochromatic infrared energy (MIRE) on diabetic wound healing. Fifteen diabetic rats were given MIRE intervention on their skin wounds located on the dorsum and compared with 15 control diabetic rats. Assessments were conducted for each group at weeks 1, 2 and 4 post wounding (five rats at each time point) by calculating the percentage of wound closures (WCs) ...

Enteroatmospheric fistulae (EAF) - unnatural connections between the bowel and the outside environment - are a feared complication of major abdominal operations. EAF pose a life-threatening risk to patients already weakened by surgical insult by altering fluid and electrolyte balance and fostering malnutrition. The authors describe a method of wound management for a 64-year-old morbidly obese...