In this paper we present a simple model for satellite constellations with polar orbits and inter-satellite links. This model is used to propose and study two algorithms for routing and re-routing communications, which aim at improving the quality of service for long communications. In order to study these algorithms, we have developed a satellite constellation simulator. Some of its results

Development of ascending aortic dilatation (AAD) in about 10 % of patients operated for aortic valve disease (AVD) is probably based on intrinsic pathology of the aortic wall. This may involve an abnormality in the process of extracellular matrix remodelling. The present study evaluated the serum levels of specific metalloproteinases (MMP-2 and MMP-9) and investigated the gene for transforming ...

BACKGROUND AND PURPOSE Multidetector-row CT (MDCT) is emerging as a new tool for diagnosing aortic atherothrombotic disease (AAD). We elucidated whether MDCT-detected AAD is associated with an increased risk of early ischemic lesion recurrence on diffusion-weighted MRI after ischemic stroke. METHODS A consecutive series of patients with acute ischemic stroke confirmed using diffusion-weighted...

BACKGROUND Astragali radix Antiasthmatic Decoction (AAD), a traditional Chinese medication, is found effective in treating allergic diseases and chronic cough. The purpose of this study is to determine whether this medication could suppress allergen-induced airway hyperresponsiveness (AHR) and remodeling in mice, and its possible mechanisms. METHODS A mouse model of chronic asthma was used to...

6 [1] We present evidence for the existence of an Australian-Antarctic Mantle Anomaly 7 (AAMA), which trends northwest-southeast (NW-SE) through the Australian-Antarctic 8 Discordance (AAD) on the Southeast Indian Ridge (SEIR), is confined to the upper 9 120 km of the mantle beneath the AAD, and dips shallowly to the west so that it extends to 10 a depth of about 150 km west of the AAD. Average...

Alzheimer's disease (AD) is a neurodegenerative disease that proceeds with the age-dependent neuronal loss, an irreversible event which causes severe cognitive and psychiatric devastations. In the present study, we investigated whether the compound, AAD-2004 [2-hydroxy-5-[2-(4-trifluoromethylphenyl)-ethylaminobenzoic acid] which has anti-oxidant and anti-inflammatory properties, is beneficial f...

Mice sensitized to ovalbumin (OVA) develop allergic airway disease (AAD) with short-term daily OVA aerosol challenge; inflammation resolves with long-term OVA aerosol exposure, resulting in local inhalational tolerance (LIT). Cbl-b is an E3 ubiquitin ligase involved with CD28 signaling; Cbl-b(-/-) effector T cells are resistant to regulatory T cell-mediated suppression in vitro and in vivo. The...

This paper provides a review of the largest studies (over period 2017 to 2022) on cost-effectiveness analysis recommended treatment algorithms for Clostridioides difficile infection in patients with antibiotic-associated diarrhea (AAD), including pseudomembranous colitis. The showed that professional medical societies Russia, EU and US as well meta-analyses consistently consider vancomycin most...

BACKGROUND Steroid-insensitive endotypes of asthma are an important clinical problem and effective therapies are required. They are associated with bacterial infection and non-eosinophilic inflammatory responses in the asthmatic lung. Macrolide therapy is effective in steroid-insensitive endotypes, such as non-eosinophilic asthma. However, whether the effects of macrolides are due to antimicrob...

CONTEXT Autoimmune Addison's disease (AAD) is a rare but highly heritable condition. The BACH2 protein plays a crucial role in T lymphocyte maturation, and allelic variation in its gene has been associated with a number of autoimmune conditions. OBJECTIVE We aimed to determine whether alleles of the rs3757247 single nucleotide polymorphism (SNP) in the BACH2 gene are associated with AAD. DE...