T he myelodysplastic syndromes (MDS) are a heterogeneous group of malignant clonal diseases of bone marrow stem and progenitor cells ranging clinically from mild asymptomatic anemia or other cytopenias to rapid transformation to acute leukemia. The early stages of MDS are characterized by dysplasia and increased apoptosis of bone marrow cells resulting in the characteristic pattern of bone marr...

in this research, a new control policy for the acceptance sampling problem is introduced. decision is made based on the number of defectives items in an inspected batch. the objective of the model is to find a constant control level that minimizes the total costs, including the cost of rejecting the batch, the cost of inspection and the cost of defective items. the optimization is performed by ...

In this paper, the effect of non-normality on sampling plan using Yule’s model (second order auto regressive model {AR (2)}) represented by the Edgeworth series is studied for known $sigma$. The effect of using the normal theory sampling plan in a non-normal situation using Yule’s model is studied by obtaining the distorted errors of the first and second kind. As one will be interes...

myelodysplastic syndrome (mds), is a group of heterogeneous disorders of hematopoietic stem cell colonies which is determined by incomplete hematopoiesis in one or more cell lines. the incidence increases with age and it has less been reported among patients under 50 years of age. the commonest form of mds is sporadic, and familial occurrence of mds is rare. patients with familial mds are young...

Myelodysplastic syndromes (MDSs) are a clonal bone marrow (BM) disease characterized by ineffective hematopoiesis, dysplastic maturation and progression to acute myeloid leukemia (AML). Methylation silencing of HRK has been found in several human malignancies. In this study, we explored the association of HRK methylation status with its expression, clinical parameters and MDS subtypes in MDS pa...

the aim of this study was to empirically investigate the effect of death-awareness on state mindfulness and state integrative self-knowledge. for existentialists, confrontation with the fact of one’s personal death and tolerance of its inevitable anxiety is the most fundamental conflict of human beings. if such confrontation occurs, it leads to enhancement of one’s self-awareness. empirical tes...

The purpose of this article is to present an optimization model for designing an acceptance sampling plan based on cumulative sum of run length of conforming items. The objective is to minimize the total loss including both the producer and consumer losses. The concept of minimum angle method is applied to consider producer and consumer risks in the optimization model. Also the average number o...

Myelodysplastic syndromes (MDSs) are a heterogeneous group of hematopoietic stem cell diseases categorized by dysplasia in one or more hematopoietic cell lineages, as well as cytopenia and functional abnormalities in bone marrow cells. Several MDS classification methods have been proposed to categorize the disease and help professionals better plan in patients' treatment. The World Health Organ...

BACKGROUND Dietary pattern analysis, based on the concept that foods eaten together are as important as a reductive methodology characterized by a single food or nutrient analysis, has emerged as an alternative approach to study the relation between nutrition and disease. The aim of the present study was to compare nutritional intake and the results of dietary pattern analysis in properly match...