Journal:
:iranian journal of allergy, asthma and immunology
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reza safaralizadeh department of biochemistry, national institute of genetic engineering and biotechnology, tehran, ira
zahra-soheila soheili department of biochemistry, national institute of genetic engineering and biotechnology, tehran, ira
abdolkhaleg deezagi department of biochemistry, national institute of genetic engineering and biotechnology, tehran, ira
zahra pourpak immunology, asthma and allergy research institute, tehran university of medical sciences, tehran, ir
shahram samiei iranian blood transfusion organization research center, tehran, iran
mostafa moin immunology, asthma and allergy research institute, tehran university of medical sciences, tehran, ir
fcεri, the high affinity receptor for ige plays a critical role in triggering the allergic reactions. it is responsible for inducing mast cell degranulation and deliberation of allergy mediators when it is aggregated by allergen and ige complexes. fcεri on the mast cells consists of three subunits; α chain directly binds ige, β chain and dimmer of γ chains together mediate intracellular signali...