Following Salmonella invasion, intestinal epithelial cells release a distinct array of proinflammatory cytokines. Interleukin (IL)-6 produced by enterocytes may have anti-inflammatory and cell-protective effects, and may counteract some of the injurious effects of sepsis and endotoxemia. Recent studies in a variety of rodent models of experimental colitis by using PJ-34, a potent poly (ADP-ribo...

Angiogenesis-related treatments have a broad spectrum of potential applications ranging from cancer to macular degeneration, to wound healing. Thus, the identification of pharmacological agents that modulate new blood vessel formation has attracted much attention. In the present study, we investigated the effects of the poly(ADP-ribose) polymerase (PARP) inhibitor PJ-34 [N-(6-Oxo-5,6-dihydro-ph...

Graphs are usual data structures in Computational Biology and Chemistry. Indeed, molecules and many biological structures can easily be represented as graphs and stored in large databases. For this reason and other applications in Image Analysis for instance, a lot of exact and approximate matching algorithms have been proposed to address the problem of searching for patterns in large graphs. I...

The 3 billion genetic instructions that form a blueprint for human life have now been cataloged, but the meaning of most of those instructions remains unknown. Therefore, the practical significance of deciphering the book of human life remains murky except in one area: many new pharmaceutical drugs will soon be possible. Unfortunately, this is a mixed blessing. A raft of new drugs may benefit t...

Copyright: © 2016 Phillips JL, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. *Corresponding author: Mackenzie Campbell-Furtick, JPS Health Network, 1500 S. Main St., Fort Worth, TX 76104, United State...

[This corrects the article on p. 821 in vol. 8, PMID: 28533770.].

Streptomyces padanus strain PMS-702 is an antagonist of Rhizoctonia solani AG-4, the causal agent of damping-off of cabbage. Treatment of cabbage seeds with the culture filtrate of S. padanus strain PMS-702 was effective in reducing the incidence of damping-off of cabbage. The major active ingredient from the culture filtrate of S. padanus strain PMS-702 was purified by silica gel column chroma...

induction of extracellular proteins and cell adhesion proteins Jee-In Heo, Soo-Jin Oh, Yoon-Jung Kho, Jeong-hyeon Kim, Hong-Joon Kang, Seong-Hoon Park, Hyun-Seok Kim, Jong-Yeon Shin, Sung-Young Lee, Min-Ju Kim, Bon-Hong Min, Sung Chan Kim, Jae-Bong Park, Jaebong Kim and Jae-Yong Lee* Department of Biochemistry, College of Medicine, Hallym University, Chuncheon, Gangwon-do 200-702, Republic of K...

*Correspondence should be addressed to Ernesto Abel-Santos or Jürgen Brojatsch. EAS: Department of Chemistry, University of Nevada Las Vegas, 4505 Maryland Pkwy-Box 454003, Las Vegas, NV 89154, Tel. 702 895-2608, Fax. 702 895-4072, E-mail: [email protected]. JB: Department of Microbiology and Immunology, Albert Einstein College of Medicine, Golding 404, 1300 Morris Park Avenue, Bronx,...