It was recently demonstrated that, when coupled to N = 1 supergravity, the Dirac-Born-Infeld (DBI) action constructed from a single chiral superfield has the property that when the higher-derivative terms become important, the potential becomes negative. Thus, DBI inflation cannot occur in its most interesting, relativistic regime. In this paper, it is shown how to overcome this problem by coup...

Significant work in animal models combined with compelling studies in human patients together have begun to provide a higher resolution picture of how the immune system regulates cancer development. Currently, this immune system-tumor interaction is represented by the concept of cancer immunoediting, which emphasizes that immunity may subserve either classical cancer immunosurveillance function...

Cancer/testis (CT) antigens are named after their expression pattern as they are typically present in various types of tumors and in the germ cells of normal adult testis. Adult ovarian tissue is usually reported to be CT antigen negative. Based on the differences in female versus male gonadal development, the ovarian counterpart of the most predominant CT antigen positive testicular germ cells...

The title eremophilenolide, C(15)H(22)O(3), is a natural compound isolated from Senecio laetus Edgew. The two cis-fused six-membered rings have chair confomations and the five-membered ring has a planar envelope conformation [maximum deviation = 0.010 (1) Å]. The β-hy-droxy group participates in inter-molecular O-H⋯O hydrogen bonding, forming mol-ecular chains along the a axis.

This report summarizes progress on Washington University’s Terabit Burst Switching Project, supported by DARPA and Rome Air Force Laboratory. This project seeks to demonstrate the feasibility of Burst Switching, a new data communication service which can more effectively exploit the large bandwidths becoming available in WDM transmission systems, than conventional communication technologies lik...

Bax and Bak play a redundant but essential role in apoptosis initiated by the mitochondrial release of apoptogenic factors. In addition to their presence at the mitochondrial outer membrane, Bax and Bak can also localize to the ER. Agents that initiate ER stress responses can induce conformational changes and oligomerization of Bax on the ER as well as on mitochondria. In wild-type cells, this ...

The mixed 3-12/3-1, control problem can be motivated as a nominal LQG optimal control problem subject to robust stability constraints, expressed in the form of an 3-1, norm bound. While at the present time there exist efficient methods to solve a modified problem consisting on minimizing an q p e r b o m d of the 2 2 cost subject to the IH, constraint, the original problem remains, to a large e...