Mortalin/mtHsp70 (mitochondrial Hsp70) and HSP60 (heat-shock protein 60) are heat-shock proteins that reside in multiple subcellular compartments, with mitochondria being the predominant one. In the present study, we demonstrate that the two proteins interact both in vivo and in vitro, and that the N-terminal region of mortalin is involved in these interactions. Suppression of HSP60 expression ...

The Ocean Drilling Program (ODP) has amassed large databases (including paleontological) as a result of its research on the geology of the ocean floor. ODP has begun to present its research results in electronic proceedings that will soon completely displace paper publications. Palaeontologia Electronica (PE) has pioneered the concept of an all-electronic paleontological journal with no paper e...

The carbonic anhydrase (CA: Carbonate hydrolyase: E.C.4.2.1.1) content from the leaves and flowers of mature yarrow (Achillea millefolium), a plant believed to possess healing qualities, was purified and characterized. The purification levels were 35.58 fold in the leaves and 40.21 fold in the flowers. The optimum temperatures were 25C and 40C for the leaves and flowers, respectively, and optim...

of reduced glutathione was detected and this decrease was fo11owed by a decrease in leyels of glucose 6-phesphate. When twigs that contained depressed leyels of reduced glutathione and glucose-6-phosphate were transferred to 40C, oyercompensation for the decrease in reduced glutathione and glucose-6-phosphate occurred and the resultant surplus appeared to reflect the metabolic dysfunction in th...

Experiments were designed to determine the rate of gain of heat-tolerance for three different groups of goldfish, Carassius auratus, respectively acclimated to 4°C., 12°C., and 20°C., and subsequently moved to a temperature S°C. higher. The rate of change of heat-tolerance showed a marked difference in the three greups, twenty or more days being required for complete acclimation in the 40C. gro...

The anti-bacterial property and preservative nature of honey has been studied by evaluating the role of hydrogen peroxide in these properties, against bacterial strains isolated and identified from pasteurized milk samples. The antibacterial property of honey examined by agar incorporation assay and turbidometry, indicated a concentration dependent inhibition of bacterial growth in all catalase...

An extremely haloalkaliphilic archaeon Natrinema sp. SSBJUP-1 showing potent amylolytic and proteolytic activities was isolated from the saline alkaline Lonar Lake, India. Amylase and protease were active over the neutral to alkaline pH range from 6 to 9. Amylase was more stable over a narrower temperature range of 40-60C than the protease but had the higher optimum (55C) for activity. By contr...