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4. van Ingen J, Rahim Z, Mulder A, Boeree MJ, Simeone R, Brosch R, et al. Characterization of Mycobacterium orygis as M. tuberculosis complex subspecies. Emerg Infect Dis. 2012;18:653–5. http://dx.doi. org/10.3201/eid1804.110888 5. Gey van Pittius NC, Perrett KD, Michel AL, Keet DF, Hlokwe T, Streicher EM, et al. Infection of African buffalo (Syncerus caffer) by oryx bacillus, a rare member of ...

This study tested the effectiveness of fact-check format (regular vs. satirical) to refute different types false information. Specifically, we conducted a pre-registered online survey experiment (N = 849) that compared effects regular fact-checkers and satirist refutations in response mis- disinformation about crime rates. The findings illustrated both fact-checking formats – factual satirical ...

Recessive dystrophic epidermolysis bullosa (RDEB) is a severe mucocutaneous disease caused by loss-of-function mutations to the collagen VIIa (COL7A1) gene that encodes type VII peptide (C7). Previously, we used programmable nucleases and DNA base editors (BE) repair COL7A1 through homology-directed (HDR) or deamination, respectively. These efforts represent personalized medicine approach; howe...

UNLABELLED Breast-specific γ-imaging (BSGI) is a physiologic imaging modality that can detect subcentimeter and mammographically occult breast cancer, with a sensitivity and specificity comparable to MRI. The purpose of this study was to determine the incremental increase in breast cancer detection when BSGI is used as an adjunct to mammography in women at increased risk for breast cancer. ME...

BACKGROUND Drosophila Neuroglian (Nrg) and its vertebrate homolog L1-CAM are cell-adhesion molecules (CAM) that have been well studied in early developmental processes. Mutations in the human gene result in a broad spectrum of phenotypes (the CRASH-syndrome) that include devastating neurological disorders such as spasticity and mental retardation. Although the role of L1-CAMs in neurite extensi...

The PRAETORIAN trial showed that the subcutaneous implantable cardioverter defibrillator (S-ICD) is noninferior to transvenous ICD (TV-ICD) with respect device-related complications and inappropriate shocks in a conventional population. Nevertheless, type of underlying mechanism for differ between devices. Earlier studies have reported decrease quality life (QoL) patients or complications. It u...