Nitric oxide (NO) has been demonstrated to enhance memory formation in experimental animals. However, the effect of NO precursor, L-arginine has never been tested on the memory impairing action of the aniepileptic drug, phenobarbitone independently and concurrently with the convulsant, picrotoxin (PCT). In view of this, in the present study, rats that acquired the shock avoidance task were trea...

background : in this study, the inhibitory effect of ethylene dichloride (edc) on biodegradation was investigated using the specific methanogenic activity (sma) test of anaerobic biomass. methods: in the present study, 40 sma tests were performed using 120-ml vials in batch mode. substrate, biomass, and biogas occupied 66%, 17%, and 17% (v/v) of the volume of each vial, respectively. the durati...

OBJECTIVE To evaluate the acute toxicity of 2-deoxy-D-glucose (2DG) by oral (p.o.) and intravenous (i.v.) routes, and also the cardio-respiratory effects following high doses of 2DG in animal models. METHODS The LD50 of 2DG (in water) was determined in rats and mice by p.o. route and in mice by i.v. route. The effect of 2-DG (250 mg/kg, 500 mg/kg, and 1000 mg/kg, i.v.) was studied on various ...

Background: Gastroschisis is a congenital malformation characterized by the extrusion of the fetal bowel during intrauterine life, secondary to a defect in anterior abdominal wall. Objective: To establish an experimental model of gastroschisis in fetuses of rats exposed to acetylsalicylic acid (ASA), during pregnancy. Methods: Wistar rats were treated with an oral single ASA dose of 50, 500, 75...

the use of such biostimulants as humic materials has recently become common in turf management operations. these products have been used to help the establishment of turfgrass and to enhance the turf stress tolerance capacity. this experiment was aimed at studying the effect of humic acid on some growth factors in turf grass. it was carried out in a factorial randomized complete block design (r...

Microbial fuel cell (MFC) with a modified anode is one of the new methods to increase MFC efficiency. This study synthesized an cobalt manganese oxide (MnCo2O4@CF) on carbon felt (CF) by easy hydrothermal method and binder-free. Chemical oxygen demand (COD) was measured without diclofenac (DCF). According SEM results, MnCo2O4 uniformly dispersed electrode surface. Moreover, maximum power densit...

OBJECTIVES Rituximab is an effective treatment in patients with established rheumatoid arthritis (RA). The objective of the IMAGE study was to determine the efficacy of rituximab in the prevention of joint damage and its safety in combination with methotrexate (MTX) in patients initiating treatment with MTX. METHODS In this double-blind randomised controlled phase III study, 755 MTX-naïve pat...