Fever is a common response to inflammation and infection. The mechanism involves prostaglandin E2 (PGE2)-EP3 receptor signaling in the hypothalamus, which raises the set point of hypothalamic thermostat for body temperature, but the lipid metabolic pathway for pyretic PGE2 production remains unknown. To reveal the molecular basis of fever initiation, we examined lipopolysaccharides (LPS)-induce...

Pyridine, a suspected genotoxic and formaldehyde, a potent carcinogen, are present in several industrial wastewater including commercial solvent, resin and pesticide manufacturing industries. The extent of pyridine and formaldehyde toxicity in aquatic organisms is unknown. Therefore, in present study the toxicity of pyridine and formaldehyde were investigated in artificial aquatic ecosystem (mi...

In vitro clonal multiplication of apple rootstock MM 111 using axillary buds and shoot apices were carried out. Vegetative axillary buds of the size of 0.2-2.0 cm and shoot apices measuring 4 mm in length were initiated to shoot proliferation on MS medium supplemented with BA (0.5 - 1.0 mgl(-1)), GA3(0.5 mgl(-1)), with or without IBA(0.05 - 0.1 mgl(-1)). Small size explants showed less phenol e...

frequency of somaclonal variation in embryogenic calli and plants of olea europaea l cv.kroneiki derived from somatic embryogenesis were examined by randomly amplified polymorphic dna (rapd) analysis. radicle and cotyledon (proximal part) of mature zygotic embryo were cultured in omc medium supplemented with iba (5 mgl-1) and 2-ip (0.5 mgl-1). somatic embryogenesis was induced in calli of radic...

Fatty acid amide hydrolase (FAAH) and monoglyceride lipase (MGL) catalyse the hydrolysis of the endocannabinoids anandamide and 2-arachidonoyl glycerol. We investigated their ultrastructural distribution in brain areas where the localization and effects of cannabinoid receptor activation are known. In the hippocampus, FAAH was present in somata and dendrites of principal cells, but not in inter...

In vivo targeting of C-type lectin receptors is an effective strategy for increasing antigen uptake and presentation by dendritic cells (DCs). To induce efficient immune response, glycosylated tumor-associated Tn antigens were used to target DCs through binding to macrophage galactose-type lectin (MGL). The capacity of Tn-glycosylated antigens-and the multiple antigenic glycopeptide Tn3 therape...

An investigation was carried out to decipher the effect of genotypes and concentrations growth regulators for callus induction subsequent plant regeneration from mature seeds rice. Two local rice cultivars viz. Nayanmony Kalomona two 2, 4-D NAA were used evaluate their performance. The cultured under aseptic condition onto MS basal medium at varying combinations (1.0, 1.5 2.0 mgL- 1) (0.0, 0.5 ...

abstract an investigation was performed in a commercial orchard in shiraz to study the effect of time of application of cuso4 and streptomycin on quality and seedlessness of grapevine (vitis vinifera l. cv. ‘siyah-e-shiraz’). the experiment was conducted as completely randomized block design with 3 replications. plants were treated with 25 mgl-1 cuso4. 5h2o and 200mgl-1 streptomycin 2,4 and 6 d...