Injury of renal tubular epithelial cells can induce acute renal failure and obstructive nephropathy. Previous studies have shown that administration of insulin-like growth factor-1 (IGF-1) ameliorates the renal injury in a mouse unilateral ureteral obstruction (UUO) model, whereas the underlying mechanisms are not completely understood. Here, we addressed this question. We found that the admini...

The lepidopteran-specific, insecticidal crystal proteins of Bacillus thuringiensis vary in toxicity to different species of lepidopteran larvae. We report studies of CryIA(a) and CryIA(c), two related proteins that have different degrees of toxicity to Heliothis virescens yet very similar degrees of toxicity to Manduca sexta. The amino acid differences between these proteins are located primari...

A major barrier to successful antitumor vaccination is tolerance of high-avidity T cells specific to tumor antigens. In keeping with this notion, HER-2/neu (neu)-targeted vaccines, which raise strong CD8(+) T cell responses to a dominant peptide (RNEU(420-429)) in WT FVB/N mice and protect them from a neu-expressing tumor challenge, fail to do so in MMTV-neu (neu-N) transgenic mice. However, tr...

T cell costimulation via OX40 is known to increase CD4+ T cell expansion and effector function and enhances the development of T cell memory. OX40 costimulation can also prevent, and even reverse, CD4+ T cell anergy. However, the role of OX40 in CD8+ T cell function is less well defined, particularly in the setting of immune tolerance. To determine the effects of OX40 costimulation on the induc...

The natural history of aortoarteritis was studied in 88 patients (54 women and 34 men). The average age was 24.0±8.8 years at onset of symptoms and 28.3±9.9 years at diagnosis. The follow-up period was 83.6± 74.4 months from onset and 33.2±37.0 months from diagnosis. Ten patients (11.4%) died during follow-up (0.016 deaths/patient year), and 22 patients (25%) suffered major nonfatal events (0.0...

Light diffraction is one of the most widely used techniques for measuring the size of a wide range of particles from very fine to very coarse. The method is popular because it is quick and easy to use, flexible, and it can be adapted to measure samples presented in various physical forms. The method depends on the analysis of the diffraction pattern produced when particles are exposed to a coll...

This is, we believe, the final version of a chaper for the Handbook of Logic and the Foundations of Computer Science, vol.IV, Oxford University Press. It surveys a range of models for parallel computertation to include interleaving models like transition systems, synchronisation trees and languages (often called Hoare traces in this context), and models like Petri nets, asynchronous transition ...

I. UNIQUE IDENTIFIERS ............................................................... 421 A. James Grimmelmann and @grimmelm .................................. 422 B. Unique Identifiers ................................................................. 424 C. Other Examples .................................................................... 426 II. CONSEQUENCES ....................................

Formate dehydrogenase, NADH dehydrogenase, a quinone and a b-type cytochrome characterized by maxima at 429 and 560 nm are shown to participate in the tetrathionate redox chain of Citrobacter.

O118.429onNovemer5,2017bygestht://jcm.sm.rg/Downladedfom