The gamma chain of human plasma fibrinogen is heterogeneous with three forms differing in length at the C-terminus. Alternative RNA splicing produces two gamma chain mRNAs encoding gamma 50 and gamma 57.5 polypeptides, while fibrinogen gamma 55 is produced by post-translational modification of the gamma 57.5 chain. The composition of purified variant gamma chain fibrinogens, which comprise 10% ...

BACKGROUND Because pneumococcal serotype 6C was previously not distinguished from serotype 6A, the impact of the 7-valent pneumococcal conjugate vaccine (PCV7) on the carriage of serotype 6C is unknown. METHODS The nasopharyngeal (NP) prevalence of the 6C serotype was determined using 1326 pneumococcal isolates collected from 7 cohorts of Massachusetts children between 1994 and 2007. Initiall...

OBJECTIVE To determine the prevalence and subtypes of hypertension among semi-urban residents in south-western Nigeria. METHODS All adults aged 18 years or older in 10 semi-urban communities were recruited for the study. The blood pressure (BP) reading taken with a validated electronic BP monitor after at least 10 minutes of rest was used in the analysis. Hypertension was defined as BP ≥ 140/...

SETTING Ten primary health clinics in rural Thyolo District, Malawi. OBJECTIVE Tuberculosis (TB) is a common initial presentation of human immunodeficiency virus (HIV) infection. We investigated the time from TB symptom onset to HIV diagnosis to describe TB health-seeking behaviour in adults newly diagnosed with HIV. DESIGN We asked adults (18 years) about the presence and duration of TB s...

We developed a Gene Annotation Easy Viewer (GAEV) that integrates the gene annotation data from the KEGG (Kyoto Encyclopedia of Genes and Genomes) Automatic Annotation Server. GAEV generates an easy-to-read table that summarizes the query gene name, the KO (KEGG Orthology) number, name of gene orthologs, functional definition of the ortholog, and the functional pathways that query gene has been...

Problem statement: The study of Malaysian Arabic phoneme is rarely found which make the references work difficult. Specific guideline on Malaysian subject is not found even though a lot of acoustic and phonetics research has been done on other languages such as English, French and Chinese. Approach: This study discussed about the correct and simplest way of Arabic phonemes pronunciation in Mala...

C-reactive protein (CRP) is an acute phase reactant the concentration of which increases significantly following tissue injury or inflammation. It is present in the albumin fraction of the serum of patients and is antigenic upon injection into rabbits. We report here the development of a local latex reagent coated with rabbit anti-CRP. For this purpose CRP was isolated from pooled sera of patie...

This paper outlines a qualitative research investigation of intranets and their capacity to facilitate organizational knowledge work. The study calls for an alternate view to intranet systems development and evaluation, one that tempers a predominant focus on information content and technology concerns with an awareness of the information needs, uses, and contexts of organizational participants...