cytokines have important roles in the control of bacterial and viral infections such as hiv-1. interleukin 17 which is secreted by th17 is one of these cytokines with a special role in controlling microbial infections. in the present study, adjuvant activity of alum and naloxone mixture has been studied on immune responses, especially il-17 cytokine. naloxone and alum adjuvant are mixed with 10...

one of the most significant issues in pharmaceutical industries, prior to commercializationof a pharmaceutical preparation is the “preformulation” stage. however, far too attention hasbeen paid to verification of the software assisted statistical designs in preformulation studies.the main aim of this study was to report a step by step preformulation approach for a semisolidpreparation based on ...

statement of problem: calcium hydroxide which is commonly used as an intracanal medicament, changes the ph of dentin and periradicular tissues to an alkaline ph. in some clinical situations, endodontic reparative cements like calcium enriched mixture cement are used after calcium hydroxide therapy. however, the alkaline ph may affect the physical properties of this cement. objectives: this stud...

objective(s):drug delivery through the skin can transfer therapeutic levels of drugs for pharmacological effects. analgesics such as nsaids have gastrointestinal side effects and topical dosage forms of these drugs are mainly preferred, especially for local pains. meloxicam is one of nsaids with no topical form in the market. in this research, we attempted to quantify the skin permeation of a m...

in this study, 4 different food diets were examined for feeding white worm which were studied. results showed that suitable moisture for growth and development of white worm was 50 - 70 % that their biomass reached to a 675 g/m2 during 90 days. but it decreased significantly at moisture lower than 45 % and upper than 65 %. white worm had similar growth both in acidic and basic area. white worm ...

in this work, a molecular dynamics simulation of the transport of water - methanol mixture through the single wall carbon nanotube (swcnt) is reported. methanol and water are selected as fluid molecules since water represents a strongly polar molecule while methanol is as an intermediate between polar and strongly polar molecules. some physical properties of the methanol-water mixture such as r...