A simple, sensitive, and accurate RP-HPLC coupled with UV detector method was developed and validated for simultaneous determination of matrine and tinidazole in compound lotion. The chromatographic separation of the two compounds was carried out with a SinoChoom ODS-BP C18 column (5  μ m, 4.6 mm × 200 mm) analytical column, using a mobile phase consisting of 0.025 mol/L potassium dihydrogen ph...

Canine otitis externa and cutaneous pyoderma are common problems that are often associated with Staphylococcus intermedius, Pseudomonas aeruginosa, and Malassezia pachydermatis. In vitro activity of two topical products against these organisms isolated from canine referral patients were evaluated. Organisms were grown and diluted to a concentration equivalent to 10(7) colony-forming units (CFU)...

Background: A neem-based conditioner lotion (ONC) used against head lice was previously tested clinically and shown to be relatively ineffective. To improve the activity against lice and their eggs, it was reformulated into a silicone vehicle (NNC) as part of a project to improve pediculicidal medical devices. An ultrasound nit comb was also developed to be used in conjunction with the neem lot...

PURPOSE To evaluate and characterize the wound healing process profile induced by allantoin incorporated in soft lotion oil/water emulsion using the planimetric and histological methods. METHODS Female Wistar rats (n=60) were randomly assigned to 3 experimental groups: (C) control group-without treatment; (E) group treated with soft lotion O/W emulsion excipients; (EA) group treated with soft...

Following the publication of the original article [1], an error was noticed by the authors. The statistics shown in Figure Two do not accurately reflect the results outlined in the text. To correctly reflect the text, the “subjects with/without live lice” graph in Fig. 2 (Fig. 1 here) should state 98.2 % for day 7 and 96.5 % for day 14 (at current the graph states 90.2 % for day 7 and 90.5 % fo...

Avocado (Persea a mericana) contains lot of vitamin A, B , C and E which is good to be used in skin care. One the cosmetics for skincare lotion, liquid emulsion consisting oil p hase water phase stabilized by emulgator . Lotion protect maintain moisture level The purpose t his research was formulate evaluate lotion order assure physical characteristic stability were accepted accord ing Handbook...

Valeriana glechomifolia, a native species from southern Brazil, presents antidepressant-like activity and diene valepotriates (VAL) contribute to the pharmacological properties of the genus. It is known that depression can develop on an inflammation background in vulnerable patients and antidepressants present anti-inflammatory properties. We investigated the effects of VAL (10 mg/kg, p.o.) on ...

Excipient allergies are rare and difficult to diagnose. Carboxymethylcellulose (CMC, carmellose sodium) is an anionic water-soluble polymer derived from native cellulose, that is, used as excipient. Here, we report a case of urticaria caused by the CMC in lidocaine jelly dimethicone drops, which had for upper gastrointestinal endoscopy. widely pharmaceutical preparations, food additives, other ...