BACKGROUND Chronic Hepatitis B (CHB) is accompanied by inflammation of liver because of infection with Hepatitis B Virus (HBV). Previous studies revealed an inverse association between vitamin D and HBV DNA levels. OBJECTIVES The current study aimed to investigate the levels of 25 (OH) D3 (the steady form of vitamin D), miR-378 and HBV DNA in the patients with CHB. PATIENTS AND METHODS One ...

MicroRNAs (miRNAs) are small fragments of single-stranded RNA containing 18-24 nucleotides, and are generated from endogenous transcripts. MicroRNAs function in post-transcriptional gene silencing by targeting the 3'-untranslated region (UTR) of mRNAs, resulting in translational repression. We have developed a system to study the role of miRNAs in cell differentiation. We have found that one of...

Cancer cachexia is associated with pronounced adipose tissue loss due to, at least in part, increased fat cell lipolysis. MicroRNAs (miRNAs) have recently been implicated in controlling several aspects of adipocyte function. To gain insight into the possible impact of miRNAs on adipose lipolysis in cancer cachexia, global miRNA expression was explored in abdominal subcutaneous adipose tissue fr...

Even though K-12 education policy has become an increasingly salient topic in the United States, few individuals understand the diverse arrangements states have devised to govern America's schools. Describing that variability and then using it to explain student academic success and state policy production is this paper’s empirical goal. That focus provides a new test of institutional theories ...

Tzu-Chieh Wei, Kae Nemoto, Paul M. Goldbart, Paul G. Kwiat, William J. Munro, and Frank Verstraete Department of Physics, University of Illinois at Urbana-Champaign, 1110 West Green Street, Urbana, Illinois 61801-3080 Informatics, Bangor University, Bangor LL57 1UT, United Kingdom Hewlett-Packard Laboratories, Filton Road, Stoke Gifford, Bristol, BS34 SQ2, United Kingdom Department of Mathemati...

Rb(+/+):Rb(-/-) chimeric mice are healthy until early in adulthood when they develop lethal pituitary tumors composed solely of Rb(-/-) cells. In an effort to delineate the minimal structures of the retinoblastoma protein necessary for RB tumor suppression function, chimeric animals derived from stably transfected RB(-/-) embryonic stem (ES) cells were generated. One such ES cell transfectant e...

INTRODUCTION.............................................................. 373 CLASSIFICATION ......... 374 DESCRIPTION OF F. NECROPHORUM. 376 Cellular Morphology ................................... 376 Lipopolysaccharide ................................... 376 Toxins ................................... 377 Biochemical Properties ........ ........................... 378 Serological Properties ....

393 amino acids; 53 kDa protein; numerous post translational modifications: phosphorylation, acetylation, ubiquitination, sumoylation, neddylation. Contains from N-term to C-term, a transactivation domain (1-42), a Proline rich domain (63-97), a specific DNA binding domain (102-292), 3 nuclear localization signals (305-322), a tetramerization domain that include a nuclear export signal (325-355...

MicroRNAs (miRNAs) are short, single-stranded non-coding RNAs that repress their target genes by binding their 3' UTRs. These RNAs play critical roles in myogenesis. To gain knowledge about miRNAs involved in the regulation of myogenesis, porcine longissimus muscles were collected from 18 developmental stages (33-, 40-, 45-, 50-, 55-, 60-, 65-, 70-, 75-, 80-, 85-, 90-, 95-, 100- and 105-day pos...