In the context of the public health surveillance, the situation room might be playing an interesting role as a strategy for early alert and follow-up of a specific public health event and its determinants. The implementation and proper functioning of an influenza situation room monitoring seasonal and pandemic influenza or any other public health event could help to mitigate the impact of the n...

The selection of yeasts intended as starters for table olives is a complex process, including a characterization step at laboratory level and a validation at lab level and factory-scale. The characterization at lab level deals with the assessment of some technological traits (growth under different temperatures and at alkaline pHs, effect of salt, and for probiotic strains the resistance to pre...

UNLABELLED Minimally invasive approach for groin hernia treatment is still controversial, but in the last decade, it tends to become the standard procedure for one day surgery. We present herein the technique of laparoscopic Trans Abdominal Pre Peritoneal approach (TAPP). The surgical technique is presented step-by step;the different procedures key points (e.g. anatomic landmarks recognition, d...

We present, by means of a simple example, a comprehensive step-by-step procedure to consistently derive a pH model of aquatic systems. As pH modelling is inherently complex, we make every step of the model generation process explicit, thus ensuring conceptual, mathematical, and chemical correctness. Summed quantities, such as total inorganic carbon and total alkalinity, and the influences of mo...

PRINCIPLES Optimal management of perforated appendicitis with perityphlitic phlegmon or abscess formation is controversial. The aim of the study was to assess the outcome after a two-step procedure to treat patients with perityphlitic abscess formation. METHODS We retrospectively assessed prospectively collected data from a single-centre database that included adult patients who had appendici...

brovascular occlusive disease, or from peripheral arterial occlusive disease. As shown in Table 1, there were distinctly higher homocysteine concentrations for seropositive subjects in subgroups of age, renal function, smoking status, and MTHFR gene mutations. These variables influencing serum homocysteine, as well as vitamin B 6 , vitamin B 12 , and folic acid, are moreover homogeneously (not ...

This paper considers p-value based step-wise rejection procedures for testing multiple hypotheses. The existing procedures have used constants as critical values at all steps. With the intention of incorporating the exact magnitude of the p-values at the earlier steps into the decisions at the later steps, this paper applies a different strategy that the critical values at the later steps are d...

Ribonucleases are considered as promising tools for anticancer treatment due to their selective cytotoxicity against tumor cells. We investigated a new RNase from Bacillus altitudinis termed BALNASE (B. altitudinis RNase). Balnase is a close homolog of the well-known cytotoxic binase, differing by only one amino acid residue: nonpolar hydrophobic alanine at position 106 in the balnase molecule ...

This study deals with modeling of production risk by means of a two-step procedure. In contrast to earlier studies of production risk, we do not immediately adopt restrictive functional forms for the risky production technology. We first test for the presence of production risk. If production risk is found to be present, the mean and risk functions are estimated separately. This allows the use ...