Some new 3-acetyl-5-(3-chloro-1-benzo[b]thiophen-2-yl)-2-substituted phenyl-2,3-dihydro-1,3,4-oxadiazoles and 2-(3-chloro-1-benzo[b]thiophen-2-yl)-5-substituted phenyl-1,3,4-oxadiazoles have been synthesized and evaluated for antimicrobial activity. Initially, 3-chloro-1-benzo[b]thiophene-2-carbonyl chloride (1) was prepared from cinnamic acid in the presence of chlorobenzene and thionyl chlori...

In the title compound, phenyl (S)-2-[(S)-(1-{2-[(S)-(1-{[(tert-but-oxy)carbon-yl]amino}-bicyclo-[2.2.2]octan-2-yl)formamido]-propanamido}-bicyclo-[2.2.2]octan-2-yl)formamido]-3-phenyl-propano-ate chloro-form monosolvate, C42H56N4O7·CHCl3, the α,β-hybrid peptide contains two non-proteinogenic amino acid residues of (S)-1-amino-bicyclo-[2.2.2]octane-2-carb-oxy-lic acid [(S)-ABOC], two amino acid ...

Abstract The synthesis and structural characterization of N -(6-methoxypyridin-3-yl)-4-(pyridin-2-yl)thiazol-2-amine mono-hydrobromide monohydrate ( 3 ) -(6-methoxypyridin-3-yl)-4-(pyrazin-2-yl)thiazol-2-amine 0.35 methanol solvate 4 are reported. crystal structures (monoclinic, space group P 2 1 / n , Z = 4) group, C 2/ c 8) feature ,4-diheteroaryl 2-aminothiazoles showing similar molecular co...

2-Cyano-3-(1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl)acrylamide (3) was synthesized in 90% yield from condensation of equimolar equivalents 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carbaldehyde (1) and 2-cyanoacetamide (2) boiling ethanol under basic condition for 45 min. The structure 3 determined using NMR spectroscopy single crystal X-ray diffraction.

A novel pyrazolo-enaminones, bipyrazoles and bipyrazolopyridines from 1-(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)butane-1,3-dione 4-methyl-2-phenyl-2H-pyrazolo[3,4-b]pyridine-3,6(3aH,7H)-dione have been synthesized by assisted heating with microwave radiation without any catalyst. The pyridine pyrazole ring formation has developed easily accessible enamino keto esters formylation followed i...

In the title compound, trans,trans-[μ-(m-phenyl-ene)bis-(ethyne-1,2-di-yl)]bis-[chlorido(1,4,8,11-tetra-aza-cyclo-tetra-deca-ne)cobalt(III)]-trans,trans-[μ-(5-bromo-m-phenyl-ene)bis-(ethyne-1,2-di-yl)]bis-[chlorido(1,4,8,11-tetra-aza-cyclo-tetra-deca-ne)cobalt(III)]-tetra-phenyl-borate-acetone (0.88/0.12/2/4), [Co(2)(C(12)H(4))Cl(2)(C(10)H(24)N(4))(2)](0.88)[Co(2)(C(10)H(3)Br)Cl(2)(C(10)H(24)N(...

A series of novel substituted N-(3-acetyl-2-oxoquinolin-1(2H)-yl)benzamide (AJQC1AJQC12) have been synthesized upon refluxing 3-acetyl-1-amino-quinolin-2-one and substituted benzoic acid in the presence of dry redistilled pyridine and silicon tetrachloride as coupling agent. 3-acetyl-1-amino-quinolin-2-one (AJQ1-AJQ12) were synthesized from substituted 3-acetyl coumarin upon refluxing with hydr...