نتایج جستجو برای: 2865
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The primary sequences of most proteins encode both the structure and the dynamics of the folding process. Unfortunately, it is still impossible to predict secondary and tertiary structures from primary sequences. This is because the complex folding dynamics involve structural evolution over several different time scales.1-4 Theoretical studies predict R-helix propagation on subnanosecond time s...
Full: HTML / PDF (4319K) Select Citation Preparation, Stabilization, and Bioefficacy of β-Cyclodextrin Inclusion Compounds of Chloramidophos Shanshan Zhou, Lumei Wang, Anping Zhang, Kunde Lin, and Weiping Liu pp 2708 2713; (Article) DOI: 10.1021/jf703635p Abstract Full: HTML / PDF (240K) Select Citation http://pubs3.acs.org/acs/journals/toc.page?incoden=jafcau&indecade=0&involume=56&inissue=8 (...
Normothermic machine perfusion (NMP) is emerging as a novel preservation strategy. During NMP, the organ maintained in metabolically active state that may not only provide superior preservation, but also facilitates viability testing before transplantation, and ex situ resuscitation of marginal kidney grafts. Although prevailing protocols for renal NMP are refined from initial pioneering studie...
•A class of MoSA–Nx–C nanozymes are designed and implemented•The peroxidase-like specificity is regulated by Mo–Nx coordination numbers•MoSA–N3–C single-atom nanozyme has superior exclusive activity•The mechanism coordination-number-dependent POD-like elucidated Nanozymes, which nanomaterials with enzyme-like characteristics, combine the advantages biocatalysts. Although stability durability th...
•TopBP1 assembles biomolecular condensates•Composition of TopBP1 condensates revealed by proximity proteomics•Phosphorylation induces condensation•TopBP1 condensation switches on ATR/Chk1 signaling and causes fork slowing ATR checkpoint is crucial for cellular responses to DNA replication impediments. Using an optogenetic platform, we show that TopBP1, the main activator ATR, self-assembles ext...
•CO2 hydrogenation by coupling homogeneous and heterogeneous catalysis•The reaction is conducted at low temperature with high C5+ selectivity•The activity comparable to that of the reported Ru0-catalyzed FTS CO2 a major greenhouse gas, as well cheap, nontoxic, renewable C1 resource. As clean reductant, H2 can be produced from water energy, such wind, hydro, solar energy. Production liquid fuel ...
Open AccessCCS ChemistryCOMMUNICATION1 Feb 2021Carbolong Chemistry: Planar CCCCX-Type (X = N, O, S) Pentadentate Chelates by Formal [3+1] Cycloadditions of Metalla-Azirines with Terminal Alkynes Ming Luo, Yuhui Hua, Kaiyue Zhuo, Lipeng Long, Xinlei Lin, Zhihong Deng, Zhenyang Hong Zhang, Dafa Chen and Haiping Xia Luo College Chemistry Chemical Engineering, Xiamen University, Fujian Province Goo...
Objective. Serum 14-3-3η is a novel joint-derived proinflammatory mediator implicated in the pathogenesis of rheumatoid arthritis (RA). In our study, we assessed the diagnostic utility of 14-3-3η and its association with standard clinical and serological measures. Methods. A quantitative ELISA was used to assess 14-3-3η levels. Early (n = 99) and established patients with RA (n = 135) were comp...
Objective. Serum 14-3-3η is a novel joint-derived proinflammatory mediator implicated in the pathogenesis of rheumatoid arthritis (RA). In our study, we assessed the diagnostic utility of 14-3-3η and its association with standard clinical and serological measures. Methods. A quantitative ELISA was used to assess 14-3-3η levels. Early (n = 99) and established patients with RA (n = 135) were comp...
Objective: While there are specific recommendations for pressure relieving cushions when seated in a wheelchair, there is a paucity of information regarding prescribed wheelchair cushions for persons with spinal cord injury (SCI) when traveling and not in their wheelchair seat. A questionnaire was designed to ascertain if individuals with SCI who are primarily wheelchair users utilize a prescri...
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