Background / Objectives Antidepressants constitute one of the most consumed classes of psychotropic medication. This study aims to identify a typology of users based on their individual characteristics, such as presence of a mental disorder and use of other psychotropic medication during the last year. Methods Antidepressant use for residents in the epidemiological zone of South-West Montreal a...

BACKGROUND A primary goal of asthma management is the reduction of exacerbation risk. We assessed the occurrence of oral corticosteroid-requiring exacerbations (OCS exacerbations) with long-term fluticasone/formoterol therapy, and compared it with the occurrence of similar events reported with other inhaled corticosteroid/long acting β2-agonist (ICS/LABA) combinations. METHODS The occurrence ...

OBJECTIVE Few studies have examined the effect of risk factor modifications on depression incidence. This study was to explore psychosocial risk factors for depression and quantify the effect of risk factor modifications on depression incidence in a large-scale, longitudinal population-based study. METHODS Data were from the Montreal Longitudinal Catchment Area study (N=2433). Multivariate mo...

Introduction: Little is known about the effects stem cell mobilizers (GCSF) such as neulasta (pegfilgrastim) or neupogen (filgrastim) during pregnancy, and these are often withheld from women undergoing chemotherapy during pregnancy. Materials and Methods: Women receiving chemotherapy during pregnancy were identified from the Cancer and Pregnancy Registry maintained at Cooper University Hospita...

BACKGROUND Suboptimal health status (SHS) is the third state between good health and disease. SHS is the clinical or pre-disease status of psychosomatic disease and a major global public health challenge. Although its underlying causes remain unclear, lifestyle is one of the most important factors affecting health status. METHODS A cross-sectional survey was conducted at Renmin University of ...

INTRODUCTION Hip fractures are one of the most common types of orthopaedic injury with high rates of morbidity. Currently, no study has compared risk factors and adverse events following the different types of hip fracture surgeries. The purpose of this paper is to investigate the major and minor adverse events and risk factors for complication development associated with five common surgeries ...

STUDY OBJECTIVES To study the influence of the proxy respondent on health interview surveys in children. DESIGN Cross sectional study. SETTING Children under the age of 15 years drawn from the general population of Catalonia, Spain. PARTICIPANTS The Catalan Health Interview Survey consisted of a multistage probability sample representative to the population of Catalonia. The sample size w...

BACKGROUND DNA methylation leaves a long-term signature of smoking exposure and is one potential mechanism by which tobacco exposure predisposes to adverse health outcomes, such as cancers, osteoporosis, lung, and cardiovascular disorders. METHODS AND RESULTS To comprehensively determine the association between cigarette smoking and DNA methylation, we conducted a meta-analysis of genome-wide...

A study was conducted among children under 12 years of age admitted to a rural district hospital in western Kenya to evaluate the use of blood transfusions, identify risk factors for severe anemia, and determine when transfusion improves survival of severely anemic children. A total of 2433 children were admitted to the pediatric ward during the 12-month study period; 29% (684) had severe anemi...

BACKGROUND The prevalence and clinical characteristics of osteochondritis dissecans (OCD) of the humeral capitellum among adolescent baseball players are unknown. PURPOSE To determine the OCD prevalence in adolescent competitive baseball players and to investigate the clinical characteristics of these patients. STUDY DESIGN Cross-sectional and case-control study; Level of evidence, 3. MET...