نتایج جستجو برای: 222 and 187 tonsha
تعداد نتایج: 16829975 فیلتر نتایج به سال:
هدف این پژوهش ارائۀ مدل تحلیل نقش سیاسی دولت در خصوصی‌سازی ورزش ایران بود. این مطالعه ترکیبی و از نوع طرح‌های آمیختۀ اکتشافی است. مرحلۀ اول کیفی بود. بدین منظور با مرور مباني نظري و انجام مصاحبة عميق نيمه‌ساختاريافته، اطلاعات تكميلي گردآوري، سپس داده‌های 20 مصاحبه به روش گراندد تئوری کدگذاری شد. گروه‌بندی کدها چهار مؤلفه را نشان داد. مرحلۀ دوم به‌صورت کمی و به روش مدلسازی معادلات ساختاری انجام ...
Despite recent therapeutic advances that have doubled the median survival time of patients with multiple myeloma, intratumor genetic heterogeneity contributes to disease progression and emergence of drug resistance. miRNAs are noncoding small RNAs that play important roles in the regulation of gene expression and have been implicated in cancer progression and drug resistance. We investigated th...
MicroRNAs (miRNAs) comprise a novel class of endogenous, small, noncoding RNAs that negatively regulate gene expression. Functionally, an individual miRNA is as important as a transcription factor because it is able to regulate the expression of its multiple target genes. Recently, miR-221 and miR-222 have been found to play a critical role in cancer cell proliferation. However, their roles in ...
Photocatalysis is one of the most promising technologies to achieve efficient carbon dioxide reduction reaction (CO2RR) under mild conditions. Herein, metalloporphyrin-based metal–organic frameworks (MOFs) with different metal centers, denoted as PCN-222, were utilized visible-light photocatalysts for CO2 reduction. Due combination conjugated planar macrocyclic structures metalloporphyrins and ...
MicroRNAs (miRNAs) play important roles in cancer formation and progression by suppressing the production of key functional proteins at the post-transcriptional level in a sequence-specific manner. While differential expression of miRNAs is widely observed in cancers including prostate cancer (PCa), how these miRNAs are transcriptionally regulated is largely unknown. MiRNA-221 and miRNA-222 (mi...
The amino acid-derived polyamines are organic cations that are essential for growth in all mammalian cells, but their exact roles at the molecular level remain largely unknown. Here we provide evidence that polyamines promote the translation of cyclin-dependent kinase 4 (CDK4) by the action of CUG-binding protein 1 (CUGBP1) and microRNA-222 (miR-222) in intestinal epithelial cells. Both CUGBP1 ...
Los distintos sectores –educativo, medico, laboral, empresarial, económico, social, comunicacional y cultural– entre otros, han mediatizado gran parte de sus procesos ejecución.
Tricaine (MS-222) is used commonly for sedation, immobilization, and anesthesia of poikilothermic animals. The anesthetic efficacy of different concentrations of MS-222 was compared to benzocaine and pentobarbital on the physiological changes, heart rate and ECG (electrocardiogram) parameters in the leopard frog, Rana pipiens. Loss of righting reflex (RR), loss of pain response (NR = nociceptor...
miR-221/-222 and components of the urokinase-type plasminogen activator system (uPAS) are associated with metastasis and poor prognosis in breast cancer, including the triple-negative subtype (TNBC). Modification of components of uPAS and involved miRNAs may contribute to targeted therapy for breast cancer patients. miR-221-/-222-overexpressing or miR-221-depleted cells were employed for qRT-PC...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید