نتایج جستجو برای: 212 ca

تعداد نتایج: 131398  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Taisuke Nakahama Hamza Hanieh Nam Trung Nguyen Ichino Chinen Barry Ripley David Millrine Soyoung Lee Kishan Kumar Nyati Praveen Kumar Dubey Kamal Chowdhury Yukio Kawahara Tadamitsu Kishimoto

Aryl hydrocarbon receptor (AHR) plays critical roles in various autoimmune diseases such as multiple sclerosis by controlling interleukin-17 (IL-17)-producing T-helper (TH17) and regulatory T cells. Although various transcription factors and cytokines have been identified as key participants in TH17 generation, the role of microRNAs in this process is poorly understood. In this study, we found ...

2013
Kwon J Yong Diane E Milenic Kwamena E Baidoo Young-Seung Kim Martin W Brechbiel

Recent studies have demonstrated that therapy with (212) Pb-TCMC-trastuzumab resulted in (1) induction of apoptosis, (2) G2/M arrest, and (3) blockage of double-strand DNA damage repair in LS-174T i.p. (intraperitoneal) xenografts. To further understand the molecular basis of the cell killing efficacy of (212) Pb-TCMC-trastuzumab, gene expression profiling was performed with LS-174T xenografts ...

2012
Matthias Friedrich Tobias Raum Ralf Lutterbuese Markus Voelkel Petra Deegen Doris Rau Roman Kischel Patrick Hoffmann Christian Brandl Joachim Schuhmacher Peter Mueller Ricarda Finnern Melanie Fuergut Dieter Zopf Jerry W. Slootstra Patrick A. Baeuerle Benno Rattel Peter Kufer

For treatment of patients with prostate cancer (PCa), we developed a novel T cell-engaging (BiTE) antibody designated AMG 212 or BAY2010112 that is bispecific for prostate-specific membrane antigen (PSMA) and the CD3 epsilon subunit of the T cell receptor complex. AMG 212/BAY2010112 induced target cell-dependent activation and cytokine release of T cells, and efficiently redirected T cells for ...

2011
Malia F. Mason Shu Zhang Rebecca Dyer

Count = 115 words Word Count: 2386 Address Correspondence To: Malia F. Mason 3022 Broadway Uris Hall 720 Columbia University Email: [email protected] Phone: (212) 854-1070 Fax: (212) 854 3778 Running Head: Power and Attention 2

2017
Raffaele Mazziotti Laura Baroncelli Nicholas Ceglia Gabriele Chelini Grazia Della Sala Christophe Magnan Debora Napoli Elena Putignano Davide Silingardi Jonida Tola Paola Tognini J Simon C Arthur Pierre Baldi Tommaso Pizzorusso

MicroRNAs (miRNAs) are known to mediate post-transcriptional gene regulation, but their role in postnatal brain development is still poorly explored. We show that the expression of many miRNAs is dramatically regulated during functional maturation of the mouse visual cortex with miR-132/212 family being one of the top upregulated miRNAs. Age-downregulated transcripts are significantly enriched ...

2015
A. Moshfegh A. Tehranifard

Introduction: There are many similarities between memory impairment in patients suffering from Alzheimer and animals treated by Cannabinoids. The agonists of Cannabinoid receptors affect on a variety of memories and leanings. The present study aims to investigate the role of α-1-adrenergic receptors in central region of amygdala in state-dependent learning induced by WIN55,212-2 (cannabinoid ag...

Journal: :Mediators of Inflammation 1993
K. G. Mugridge C. Becherucci L. Parente M. Perretti

Peptide 204-212 of lipocortin (LC) 5 inhibited porcine pancreatic phospholipase A(2) (PLA(2)) induced rat stomach strip contractions and ADP induced rabbit platelet aggregation in a concentration dependent manner (IC(30) of 10 muM and 400 muM, respectively). The first two amino acids are not necessary since the eptapeptide 206-212 was equipotent in both assays (IC(30) of 12.5 muM and 420 muM). ...

2016
Katarzyna Frankowiak Xingchen T Wang Daniel M Sigman Anne M Gothmann Marcelo V Kitahara Maciej Mazur Anders Meibom Jarosław Stolarski

Roughly 240 million years ago (Ma), scleractinian corals rapidly expanded and diversified across shallow marine environments. The main driver behind this evolution is uncertain, but the ecological success of modern reef-building corals is attributed to their nutritional symbiosis with photosynthesizing dinoflagellate algae. We show that a suite of exceptionally preserved Late Triassic (ca. 212 ...

1996
R. P. Vasquez C. C. Tsuei

HgBa2CaCu20~s (Hg1212.) thin films g]own epitaxially on SrTi03 (100) substrates have been chemically etched and studied with x-ray photoelectron spectroscopy (XPS). The XPS data presented here are the first on an epitaxial thin film of a mercury cuprate superconductor, the first in which signals from the superconducting phase dominate all the core level spectra, and the first to exhibit a clear...

2014
Firas S. Ahmed Xian-cheng Jiang Joseph E. Schwartz Eric A Hoffman Joseph Yeboah Steven Shea Kristin Marie Burkart Graham Barr

Corresponding Author: R. Graham Barr, MD, DrPH 622 W 168th Street, PB 9 East, Room 105 New York, NY 10032 Phone: 212-305-4895 Fax: 212-305-9349 [email protected].

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