MicroRNA-210 (miR-210), a master and pleiotropic hypoxia-microRNA, plays multiple roles in brain ischemia. However, miR-210 expression and its function in humans have not been explored. The aim of our study is to evaluate the correlation of blood miR-210 with clinical findings in acute ischemic stroke. Blood samples were obtained from stroke patients (n=112) and healthy controls (n= 60). MiR-21...

BACKGROUND MicroRNAs play important roles in regulation of the initiation and progression of AML. MiR-210 is closely related with cancer development; however, whether miR-210 expression level correlates with clinical correlation in AML is unknown. Thus, the aim of this study was to investigate the potential relationship between miR-210 expression and AML prognosis. MATERIAL AND METHODS Real-t...

BACKGROUND Primaquine (PQ) is used against relapses of vivax malaria (RVM) but several aspects about dosage are unknown, as the total effective dose (TD) in a number of days. OBJECTIVE To compare PQ regimens against RVM in randomized or non randomized controlled clinical trials (CCTs). METHODOLOGY Meta analysis. Information was sought until 31 December, 2012 in Lilacs, SciELO, PubMed (Medli...

Osteoarthritis (OA) is characterized by degradation of articular cartilage and joint inflammation. MicroRNAs have been proved to play an important role in the regulation of chondrogenesis. Previous study showed that microRNA-210 (miR-210) was probably associated with osteoarthritis, while the function of miR-210 in osteoarthritis still remains unknown. The aim of the present study was to invest...

Circulating cell-free(cf) microRNAs (miRNAs) have been reported to exist in plasma. MicroRNA-210(miR-210) is known to play important roles in the tumor hypoxic state. We hypothesized that the expression levels of cf-miR-210 in plasma would predict early clinical recurrence in melanoma patients. A direct miRNA assay on plasma (RT-qPCR-DP) was developed to improve cf-miRNA assay logistics, elimin...

High blood uric acid level is a risk factor for gout. To reduce the gout complications, patients need to measure their blood uric acid levels and take medication if necessary. Several commercial blood uric acid meters are available in the market. The aim of this study is to investigate the accuracy of two commercial blood uric acid meters, MultiSure and BeneCheck Pluse Meter, on blood uric acid...

The majority of all gas measurement used in the world today is performed by two basic types of meters, positive displacement and inferential. Positive displacement meters, consisting mainly of diaphragm and rotary style devices, generally account for lower volume measurement. Orifice, ultrasonic and turbine meters are the three main inferential class meters used for large volume measurement tod...