background: the incorporation of thallium-201 into 8-hydroxyquinoline was targeted for cell labeling due to interesting physical properties and wide availability of this nuclide as a single photon emission computed tomography (spect) radionuclide. materials and methods: thallium-201 (t1/2=3.04 d) in tl+ form was converted to tl3+ cation in presence of o3/6m hcl and di-isopropyl ether, controlle...

OBJECTIVES We measured the uptake of technetium-99m tetrofosmin (99m Tc) and thallium-201 (201 TI) in areas of healed transmural myocardial infarction and in the regions of acute peri-infarction ischemia. METHODS Anesthetised pigs with a 1-month old transmural infarction elicited by permanent ligature of the left anterior descending (LAD) coronary artery below the first branch underwent one h...

OBJECTIVE Comparison of 201Tl chloride SPECT (TI-SPECT) with 99mTc-MIBI SPECT (MIBI-SPECT) in the depiction of malignant head and neck tumors was prospectively studied. METHODS Forty-one patients with various tumors of the head and neck were included in this prospective study. Histologically, 36 patients had squamous cell carcinomas, 3 undifferentiated carcinomas, 1 transitional cell carcinom...

OBJECTIVE This study was designed to investigate the value of preoperative thallium-201 (201Tl) SPECT as a predictor of outcome in malignant glioma. METHODS From January 1990 to September 2003, 109 patients with glioma were treated with postoperative radiotherapy. Of these, 36 patients with malignant gliomas who underwent preoperative 201Tl-SPECT were included in this study (grade 3: n=14, gr...

Over the past 4 yr, we obtained 201Tl lower leg scans on 14 patients with suspected chronic exertional compartment syndrome. Qualitative assessment of the images revealed that 12 scans showed reversible compartment ischemia. Retrospective quantitation confirmed redistribution in seven of nine patients. Seven patients had surgery with partial or complete resolution of their symptoms.

In a multicenter randomized double-blind trial comparing heparin and a new fibrinolytic agent, anisoylated plasminogen streptokinase activator complex (APSAC), 231 patients presenting with a less than 5 hr acute myocardial infarction underwent a contrast angiography (CA) before the end of the first week of admission, and radionuclide cardiac blood-pool imaging and a 201Tl single photon emission...

background: radiolabeled polyclonal human immunoglubins are useful in the detection of inflammations. in this work a novel approach has been presented to use thallium-201 as a comlexed nuclide for the development of radioimmunoconjugates. materials and methods: thallium-201 (t1/2=3.04 d) in tl+ form was converted to tl3+ cation in presence of o3 in 6m hcl, controlled by rtlc/gel electrophoresis...

UNLABELLED Increased myocardial uptake of 18F-fluorodeoxyglucose (FDG) in regions with perfusion defects (perfusion-FDG mismatch) has been shown to predict functional recovery after revascularization; conversely, a concordant decrease in perfusion and FDG uptake (perfusion-FDG match) represents scar tissue (varying from subendocardial to transmural scar) that will not improve in contractile fun...