Our study analyzed 152 samples of alcoholic beverages collected from the states of São Paulo and Minas Gerais, Brazil, using gas chromatography with flame ionization detection (GC-FID) and mass spectrometry (GC-MS), Fourier transform infrared spectroscopy (FT-IR), and inductively coupled plasma atomic emission spectrometry (ICP-AES). The methanol content varied from 20 to 180 ppm in 28 samples,...

Workers are commonly exposed to mixtures or combinations of chemical agents, and these mixtures often consist of solvents. One group of solvents that has been extensively studied for its neurotoxic properties has been the ketones. However, previous research has focused on neuropathies produced by extended exposures and not on the simple pharmacokinetics or the reversible central nervous system ...

High pressure NMR spectroscopy has developed into an important tool for studying conformational equilibria of proteins in solution. We have studied the amide proton and nitrogen chemical shifts of the 20 canonical amino acids X in the random-coil model peptide Ac-Gly-Gly-X-Ala-NH2, in a pressure range from 0.1 to 200 MPa, at a proton resonance frequency of 800 MHz. The obtained data allowed the...

Based on acute and chronic inhalation studies conducted mostly in experimental animals, the target tissue for acetaldehyde has consistently been at the portal of entry with effects occurring primarily in the upper respiratory tract at lowest concentrations. The major noncancer health effects of acute exposure in humans to acetaldehyde vapors consist of irritation to the eyes, skin, and respirat...

This study was conducted to determine some pomological characteristics and macromicro nutrient contents of both leaves and fruits of 11 Feijoa genotypes (Feijoa sellowiana Berg.) selected from Sakarya Province in Turkey. For these genotypes, fruit weight, fruit length, fruit width, soluble solid content and fruit acidity values ranged between 18.57 – 40.00 g, 27.74 -59.95 mm, and 23.42-39.43 mm...

Mallard (Anas platyrhynchos) ducklings were fed nickel sulphate in their diet from day one to 90 days of age. Ducklings fed 1,200 ppm nickel began to tremor and show signs of paresis after 14 days of dosage (age) and 71% of this group died within 60 days of age. Birds fed 1,200 ppm nickel weighed significantly less (P less than 0.05) at 28 days of age than birds fed the other diets. Weights of ...

In order to investigate the involvement of cyclooxygenase (COX)-2 in oral carcinogenesis and chemoprevention for it, we examined the COX-2 expression during dimethylbenzanthracene (DMBA)-induced hamster cheek pouch carcinogenesis and the inhibitory effect of sulindac, a non-steroidal anti-inflammatory drug (NSAID), on the carcinogenesis and its derived squamous carcinoma cell line HCPC-1. From ...

Chloroform is being administered to male Osborne-Mendel rats and to female B6C3F1 mice at concentrations of 0 (negative control), 200, 400, 900 or 1800 ppm in the drinking water. Matched control groups of both species receive a volume of water identical to that consumed by the corresponding 1800 ppm groups. At this writing, the animals have completed 23 months on test. Negative control and CHCl...