Isoxazole (2a-l) and cyanopyridine (3a-l) derivatives have been prepared by condensing chalcones (1a-l) with hydroxylamine hydrochloride and malononitrile respectively. While compounds 1a-l have been synthesized by the reaction of p-(3’-chloro-2’-benzo(b)thiophenoylamino)-acetophenone with different aldehydes. All the compounds were screened for their antitubercular and antimicrobial activities...

BACKGROUND Intramuscular interferon beta-1a (IFNβ-1a), a multiple sclerosis (MS) therapy that has been commercially available for over a decade, provides a unique opportunity to retrospectively assess postmarketing data for evidence of malignancy risk, compared with relatively limited data available for more recently approved therapies. Postmarketing and claims data were analyzed to determine t...

conclusions real-time pcr and elisa showed high levels of production of 1a/jfh1 chimeric hcv in the huh7.5 cell culture. the constructed virus can be used for future studies, including the development of new hcv drugs and vaccines. background the e2 glycoprotein is an important encoded hepatitis c virus (hcv) protein that contains three different variable regions. objectives the aim of the pres...

Action recognition in surveillance video makes our life safer by detecting the criminal events or predicting violent emergencies. However, efficient action recognition is not free of difficulty. First, there are so many action classes in daily life that we cannot pre-define all possible action classes beforehand. Moreover, it is very hard to collect real-word videos for certain particular actio...

we aimed to compare the therapeutic effect of avonex (av), betaferon (be) & rebif (re) on the expanded disability status scale (edss) in multiple sclerosis (ms). ninety patients referring to farshchian hospital were entered in this study. the patients were divided into three equal groups: group 1 received av, group 2 received re and group 3 received be, and after 24 months, comparison was done ...

∗ Professor and author of correspondence, Phone: (086) 022-60204935, Fax: (086)010-950507 to 716480, Email: [email protected]. ABSTRACT As the description of design requirements at the earlier design stage is inaccurate and vague, it is difficult to figure out functional structure of a product and make sense product configuration. Therefore, it plays an important role to formally represent ...

introduction: laser phototherapy is used for the treatment of chemotherapy-induced oral mucositis in patients with leukemia, although there are limited data supporting the safety of this method. this study aimed to evaluate the effect of different doses of low-level laser on proliferation of acute myeloid leukemia (aml) cell line (kg-1a) in vitro. methods: a plastic flask containing 5,000,000 k...

aim and objectives: the hepatitis c virus (hcv) is essentially hepatotropic but virus compartment have also been found in other important extra hepatic sites. detection of hcv rna in extra hepatic reservoirs such as peripheral blood mononuclear cells (pbmcs) is important for determining of disease progression and effective treatment. the present study aimed to determining of different hcv genot...

Las disfunciones sexuales femeninas (DSF) implican una alteración significativa en el usual comportamiento femenino. El Índice de Función Sexual Femenina (FSFI) examina seis dimensiones del funcionamiento sexual la mujer (deseo, excitación, lubricación, orgasmo, satisfacción, dolor). Se trata un estudio instrumental que evalúa las propiedades psicométricas muestra no clínica 330 mujeres peruana...