Esophageal diverticulum often causes secondary dysmotility. If a diverticulum associated with a functional disorder is growing and exacerbating symptoms, surgical treatment is usually indicated [1,2]. Peroral endoscopic myotomy (POEM) was introduced by Inoue et al. in 2010 as a novel treatment technique for achalasia [3]. Here, we report our clinical experience of salvage POEM for esophageal di...

BACKGROUND AND STUDY AIMS Although peroral endoscopic myotomy (POEM) is being performed more frequently, the learning curve for gastroenterologists performing the procedure has not been well studied. The aims of this study were to define the learning curve for POEM and determine which preoperative and intraoperative factors predict the time that will be taken to complete the procedure and its d...

Citation: Kronschläger M, Stimpfl T, Ruiß M, Hirnschall N, Leisser C, Findl O. Pharmacokinetics of caffeine in the lens capsule/epithelium after peroral intake: a pilot randomized controlled study. Invest Ophthalmol Vis Sci. 2018;59:1855–1860. https://doi.org/ 10.1167/iovs.18-23963 PURPOSE. To determine the pharmacokinetics of perorally administered caffeine, a widely consumed and potent dietar...