As a major health threat, tuberculosis (TB) is resistant against the current therapeutic strategies. Increasing evidence indicates that miRNAs are implicated in various disorders by affecting specific target genes. Recently, the association of miRNAs with TB has also been established by several studies, and their potentials in the prognosis and treatment of TB have also been verified. miR-183 i...

We previously reported that miR-183 was downregulated during the direct conversion of dental pulp cells to insulin-producing cells. To further elucidate the role of miRNA regulation in dental pulp cells during this process, we examined the eff ect of miR-183 inhibition. Insulin expression was detected in induced cells 72 hours after ectopic expression of miR-183 inhibitor. The expression levels...

We evaluated the effect of frequency and amount of rumen-degradable intake protein (DIP) on urea kinetics in steers consuming prairie hay. Five ruminally and duodenally fistulated steers (366 kg of BW) were used in a 5 x 5 Latin square and provided ad libitum access to low-quality prairie hay (4.7% CP). Casein was provided daily in amounts of 61 and 183 mg of N/kg of BW (61/d and 183/d) and eve...

Les maîtrises (ou masters) en recherche design permettent aux étudiant·e·s de se spécialiser explorant un objet d’étude leur choix avec une formation axée sur démarche scientifique. À partir d’une étude cas la maîtrise mémoire (MDM) à l’École l’Université Laval, il appert qu’une certaine con...

The transcription factor EGR1 is a tumor suppressor gene that is downregulated in many cancer types. Clinically, loss of EGR1 translates to increased tumor transformation and subsequent patient morbidity and mortality. In synovial sarcoma, the SS18-SSX fusion protein represses EGR1 expression through a direct association with the EGR1 promoter. However, the mechanism through which EGR1 becomes ...

© 2009. The Authors. Licensee: OpenJournals Publishing. This work is licensed under the Creative Commons Att ribution License. ABSTRACT The objectives of this study were to assess the construct equivalence of the Minnesota Job Satisfaction Questionnaire (MSQ), and to investigate the manifestation of job satisfaction at selected organisations in South Africa. A cross-sectional survey design with...

© SINPE-GASAPE ABSTRACT: Background: Abdominal catastrophe, suture leakage and wound dehiscence are serious complications of surgical procedures. Wound infection is a frequent complication and the mortality is high due to long and difficult treatment procedures. Treatment is often difficult as a result of fistula formation, presence of necrotic and infected tissue, and complex surgical manageme...

Objective: To study the trends of socioeconomic inequalities and socioeconomic inequalities in self-perceived health in Spain between 1987 and 2001. Methods: We estimated the distribution of educational level and per capita provincial income, and the differences in lessthan-good self-perceived health by educational level and per capita provincial income in each period. Results: The percentage o...