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rapidly disintegrating oral tablets that contain disintegrants, such as microcrystalline cellulose or low substituted hydroxypropylcellulose. However, the main disadvantage of these tablets is a rough feeling in the mouth, because they are water-insoluble. To solve this problem, we used water-soluble sugars as ingredients of rapidly disintegrating oral tablets and developed a preparation method...

Understanding how producers make decisions to allot acreage among crops and how decisions about land use are affected by changes in prices and their volatility is fundamental for predicting the supply of staple crops and, hence, assessing the global food supply situation. The innovations of the present paper are estimates of monthly (i.e. seasonal) versus annual global acreage response models f...

We quantitatively analysed compensatory head reactions of flies to imposed body rotations in yaw, pitch and roll and characterized the haltere as a sense organ for maintaining equilibrium. During constant velocity rotation, the head first moves to compensate retinal slip and then attains a plateau excursion (Fig. 3). Below 500/s, initial head velocity as well as final excursion depend linearily...

The invasion of host cells by the malaria parasite Plasmodium falciparum requires specific protein-protein interactions between parasite and host receptors and an intracellular translocation machinery to power the process. The transmembrane erythrocyte binding protein-175 (EBA-175) and thrombospondin-related anonymous protein (TRAP) play central roles in this process. EBA-175 binds to glycophor...

Introduction: Bleomycins are DNA-binding biomolecules, which can be used as targeted therapy carriers when labeled with particle-emitters such as Yb-175. In this work the development of Yb-175 bleomycin (Yb-BLM) has been reported. Methods: Yb-175 chloride was obtained by thermal neutron irradiation (3 × 10 n.cm.s) of natural Yb2O3 samples at various neutron fluxes and irradiation times. The rad...