Suspensions of Eubacterium sp. strain 144, prepared from cells grown with 16-dehydroprogesterone, catalyzed the reduction of this steroid to 17-isoprogesterone at a very low rate. Modifications of the assay to optimize the pH (5.5) and increase the steroid solubility (10% [vol/vol] methanol) did not significantly enhance the reaction. However, growth of strain 144 in the presence of hemin was f...

Aortic dissection (AD) is a catastrophic disease with high mortality and morbidity, characterized with fragmentation of elastin and loss of smooth muscle cells. Although AD has been largely attributable to polymorphisms defect in the elastin-coding gene, tropoelastin (TE), other undermined factors also appear to play roles in AD onset. Here, we investigated the effects of post-transcriptional c...

The effect of pollutants on atopic eczema (AE) has been controversial; with different proposed inflammatory mechanisms in skin such as the aryl hydrocarbon (AhR), JAK/STAT pathways, oxidative stress and Carbonylated proteins (CPs). It shown that CP levels are higher dry AE lesions. Tower Hamlets Eczema Assessment (THEA) is a clinical environmental study Bangladeshi patients. Ambient exposure TH...