BACKGROUND In prostate cancer (PCa), abnormal expression of several microRNAs (miRNAs) has been previously reported. Increasing evidence shows that aberrant epigenetic regulation of miRNAs is a contributing factor to their altered expression in cancer. In this study, we investigate whether expression of miR-200c and miR-141 in PCa is related to the DNA methylation status of their promoter. ME...

STUDY OBJECTIVE To determine the prevalence of sleep-related breathing disturbances in a large cohort of school-aged and preschool-aged children of Southern Italy. DESIGN AND SETTING This cross-sectional prevalence study was designed in two phases: a screening phase aimed to identify symptomatic children from a cohort of 1,207 by a self-administered questionnaire, and an instrumental phase fo...

Bangsa Indonesia berhasil memproklamirkan kemerdekaan pada Tanggal 17 Agustus 1945, namun perjuangan belum sampai disitu. Banyak pergolakan yang terjadi sebagai ujian atas bangsa masih muda tersebut. Salah satu banyak menyita perhatian adalah gerakan Darul Islam / Tentara mencoba mendirikan sebuah negara lepas dari Negara Kesatuan Republik Indonesia. Pemerintah segera mengambil tindakan tegas d...

Saturday 5 July Administered Chloroform at King's College Hospital to a man whilst Mr. Partridge operated for necrosis of the tibia. Also to a child, 5 years old, whilst Mr. Fergusson operated for club foot. (710 } Also to a man whilst he operated for fissure of the anus. 710 Also to a young man whilst he operated for phymosis. Also to a woman whilst he removed a tumour of the breast. Also to a...

We report the discovery of a ∼ 96 s period X-ray pulsar in the direction of the Large Magellanic Cloud (LMC). The BeppoSAX X-ray spectrum is well fitted by an absorbed power-law model with photon index ∼ 0.5. The unabsorbed luminosity in the 2-10 keV energy range is ∼ 9×1035 erg s−1. The BeppoSAX position (40′′ uncertainty radius) of 1SAX J0544.1710 was found to be consistent with that of the A...