Keratinocytes proliferation is critical for the capacity to heal wounds and accumulating evidences have proved that dysregulation of microRNAs is involved in proliferation of keratinocytes. However, the molecular mechanisms remain to be completely elucidated. Here, we show that miR-136 was significantly decreased by TGF-β1 treatment in HaCaT cells and normal human epidermal keratinocytes (NHEK)...

B physics results from the Belle experiment are reviewed. Precise measurements of Cabbibo-Kobayashi-Maskawa matrix elements are made. Several decay modes are observed which will enable us to measure the CP angles, φ i in channels other than B 0 → ψK 0 modes. New rare decay modes are observed in many channels. Particular attention is paid to the first observation of the electroweak penguin-media...

OBJECTIVES Section 136 of the Mental Health Act 1983 empowers the police to detain those suspected of being mentally ill in public places, and convey them to a place of safety. In practice, accident and emergency (A&E) departments are often used. The authors assessed levels of knowledge of section 136 between A&E doctors, senior nurses, and police constables. METHODS Doctors and senior nurses...

SJG-136 (NSC 694501) is a novel DNA cross-linking agent that binds in a sequence-selective manner in the minor groove of the DNA helix. It is structurally novel compared with other clinically used DNA cross-linking agents and has exhibited a unique multilog differential pattern of activity in the NCI 60-cell line screen (i.e., is COMPARE negative to other cross-linking agents). Given this profi...

As part of a continuing and more general study of the diversity of parasites from subterranean mammals in central North America, individuals of the Plains Pocket Gopher, Geomys bursarius bursarius, were collected from 7 localities in northwestern Minnesota from September 1991 through October 1996. Arthropods collected included the fleas, Opisocrostis bruneri (4 of 124, 3.2%), Foxella ignota ign...

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