The debate on the use of antiseptics or antibiotics in the local antibacterial treatment of burns is still open. In general, it is believed that antibiotics are responsible for the selection of resistant strains, while the same cannot be said of antiseptics when both antibiotics and antiseptics are applied to lesions in insufficient concentrations. The current literature offers many studies on ...

Problem 1a. Ω = {T,H} b. Let set A = {1, 2, 3, ..., N} be the set of N balls numbered 1 to N. We have two choices for Ω. In the first choice, an outcome specifies which ball was picked first and which was picked second. With this choice, Ω = Ω1 := {(x, y) | x, y ∈ A, x 6= y}. In the second choice, an outcome only specifies the two balls that were picked, but not their order. With this choice, Ω...

Blood vessels form de novo through the tightly regulated programs of vasculogenesis and angiogenesis. Both processes are distinct but one of the steps they share is the formation of a central lumen, when groups of cells organized as vascular cords undergo complex changes to achieve a tube-like morphology. Recently, a protein termed epidermal growth factor-like domain 7 (EGFL7) was described as ...

We offer a hybrid system, which is integrated with the fuzzy system and Petri net models of discrete event system. It is convenient to users or students for building the model-level of system while in learning. We exploit the characteristics of fuzzy theory, imprecise or ambiguous information, to map the algorithm of crisp inputs and outputs. Furthermore, model problems, product a nonlinear fun...

OBJECTIVE This study explored the protective effects of the microRNA-126 (miR-126)-mediated PI3K/Akt/eNOS signaling pathway on human cardiac microvascular endothelial cells (HCMECs) against hypoxia/reoxygenation (H/R)-induced injury and the inflammatory response. METHODS Untreated HCMECs were selected for the control group. After H/R treatment and cell transfection, the HCMECs were assigned t...

Human cytochrome P450 (CYP)2A6 is responsible for the metabolic activation of tobacco-related nitrosamines, as well as the metabolism of nicotine and some pharmaceutical drugs. There are large interindividual differences in CYP2A6 activity and expression, largely attributed to genetic polymorphisms. However, the variability was observed within homozygotes of the wild-type CYP2A6 gene. In this s...

Previous studies have demonstrated that primary cultures of cardiac myocytes maintained in a complete serum-free medium contain a precursor to atrial natriuretic factor (ANF-(1-126]. The cultured cells secrete this precursor unless maintained in the presence of glucocorticoids wherein the known circulating form derived from the C-terminal of ANF (ANF-(99-126] is secreted. The present study was ...

AIM To survey practices in the diagnosis and management of latent tuberculosis infection (LTBI) in Australia and New Zealand. METHODS Infectious diseases and respiratory physicians and trainees were invited to complete an online questionnaire concerning various aspects of LTBI management. RESULTS The questionnaire was completed by 126 clinicians self-reporting regular management of LTBI. Re...

BACKGROUND Coronary artery disease (CAD) is a major problem worldwide. As an endothelium-enriched microRNA (miRNA), miR-126 has been reported to serve as a potential biomarker of acute myocardial infarction. However, the relationship between miR-126 and the severity of CAD remains unknown. This study was designed to test whether circulating miR-126 levels are associated with the severity of CAD...

AIMS Endothelial progenitor cells (EPCs) are capable of proliferating and differentiating into mature endothelial cells, and they have been considered as potential candidates for coronary heart disease therapy. However, the transition of EPCs to mesenchymal cells is not fully understood. This study aimed to explore the role of microRNA 126 (miR-126) in the endothelial-to-mesenchymal transition ...