1 Departamento de Farmacia, Facultad de Ciencias, Universidad Nacional de Colombia, A.A. 14490, Bogotá, D.C, Colombia. 571-3165000 ext. 14662 2 Instituto Universitario de Bio-Orgánca “Antonio González”, Universidad de La Laguna, Avda. Astrofísico. Francisco Sánchez 2, La Laguna, 38206, Tenerife, Islas Canarias, España 3 Instituto de Química y Fisicoquímica Biológicas, Facultad de Farmacia y Bio...

Cystic fibrosis (CF), the most common life-shortening genetic disorder in Caucasians, affects approximately 70 000 individuals worldwide. In 1998, the Cystic Fibrosis Foundation (CFF) launched the CF Therapeutics Development Network (CF-TDN) as a central element of its Therapeutics Development Programme. Designed to accelerate the clinical evaluation of new therapies needed to fulfil the CFF mi...

Article history: Received 5 June 2009 Available online xxxx Submitted by Goong Chen

cystic fibrosis (cf) is a life-limiting autosomal recessive disorder affecting principally respiratory and digestive system . it is caused by cystic fibrosis transmembrane conductance regulator (cftr) gene mutation. the aim of this study was to determine the extent of repeat numbers and the degree of heterozygosity for c.3499+200ta(7_56) and d7s523 located in intron 17b and 1 cm proximal to the...

Corrective feedback has received significant attention in English language teaching, and its role has been highly substantial. Considering the importance of corrective feedback in EFL classes, this study aimed at finding the effects of indirect and gradual CF on Iranian EFL learners' grammatical development and their beliefs toward CF. Twenty EFL learners, meeting the c...

Orally inhaled therapies are a cornerstone of lung health maintenance in CF. Topical application of drugs in the airways increases the efficacy and reduces the systemic exposure and toxicity of these agents. Most CF patients are treated with aerosolized therapies, and many take multiple inhaled drugs on a daily basis. Treatments for bronchodilation, inflammation, airway clearance and early or c...

Double disks synergy test (DDST) and combined disks test (CD) were evaluated to predict the presence of metallo-β-lactamase in 70 Pseudomonas aeruginosa isolates recovered from cystic fibrosis and non-cystic fibrosis patients. DDST(CAZ-EDTA 1 cm) and CD(IMP-EDTA) tests showed the best accuracy (94.3%). Furthermore, for other combinations, accuracy unsatisfactory was obtained.