The endogenous cannabinoid system plays an important role in the regulation of gastrointestinal function in health and disease. Endocannabinoid levels are regulated by catabolic enzymes. Here, we describe the presence and localization of monoacylglycerol lipase (MGL), the major enzyme responsible for the degradation of 2-arachidonoylglycerol. We used molecular, biochemical, immunohistochemical,...

Introduction: 2013 marks the 25 anniversary of the NASA Planetary Science Summer School (PSSS) [1], which is held every summer at the NASA Jet Propulsion Laboratory to provide postdocs and Ph.D. students with an intensive interdisciplinary experience in planetary robotic mission design under the tutelage of JPL's Advanced Projects Design Team ("Team X") [2]. This abstract summarizes the work of...

Monoglyceride lipase (MGL) hydrolyzes monoglycerides (MGs) to glycerol and fatty acids. Among various MG species MGL also degrades 2-arachidonoylglycerol (2-AG), the most abundant endocannabinoid and potent activator of cannabinoid receptors (CBR) 1 and 2. MGL-knockout (-/-) mice exhibit pronounced 2-AG accumulation, but lack central cannabimimetic effects due to CB1R desensitization. We have p...

An efficient method to transform five cultivars of tomato (Lycopersicon esculentum), Micro-Tom, Red Cherry, Rubion, Piedmont, and E6203 is reported. A comparison was made of leaf, cotyledon, and hypocotyl explants on 7 different regeneration media without Agrobacterium tumefaciens cocultivation and on 11 different media with cocultivation. Although all cultivars and explants formed callus and r...

Polar transport of the natural auxin indole-3-acetic acid (IAA) is important in a number of plant developmental processes. However, few studies have investigated the polar transport of other endogenous auxins, such as indole-3-butyric acid (IBA), in Arabidopsis. This study details the similarities and differences between IBA and IAA transport in several tissues of Arabidopsis. In the infloresce...

Cotton (Gossypium hirsutum L.) is a source of edible oil and fatty acids (FAs). In this study, embryos’ explants were cultured in MS medium with different concentration of  plant growth regulators (phytohormones) include BA, IAA, IBA, 2, 4- D and NAA, to finding the relationship of hormone and organogenesis with oil and FAs content. Oil was extracted with chloroform and methanol. FAs o...

in order to optimize the micropropagation of qare-qat (vaccinium arctostaphylus j.j.sm), samples were collected from two regions of iran (asalem and kelardasht). anderson (an) media containing different concentrations of zeatin (0, 0.5, 1, 2 and 4 mg l-1) and different levels of ph (4.5, 5 and 5.5) were compared. the in vitro shoots were transferred on an media supplemented with zeatin (1 and 2...

Plant tissue or cell culture keeps a significant role in micro-propagation in the plant production industry. Combination of 6-Benzylaminopurine (BAP) and other plant growth regulators like 1-Naphthaleneacetic acid (NAA) or Indole-3-acetic acid (IAA) or indole-3-butyric acid (IBA) was used in the most of the research in tissue culture. The study was carried out to investigate the optimization of...

Mrs. Gerber’s Lemma (MGL) hinges on the convexity of H(p ∗ H(u)), where H(u) is the binary entropy function. In this work, we prove thatH(p∗f(u)) is convex in u for every p ∈ [0, 1] provided H(f(u)) is convex in u, where f(u) : (a, b) → [0, 1 2 ]. Moreover, our result subsumes MGL and simplifies the original proof. We show that the generalized MGL can be applied in binary broadcast channel to s...