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(n = 704 066). Cumulative proportions for the total number of sectors and the total population contained within those sectors were also calculated. On the basis of these results, if 20% of the most deprived sectors in Scotland (1 205 833/4 998 202 (24%) of the population) were targeted, 41% of unemployed people and 34% of low income households would be “captured” (figure). By targeting 254 post...

Type 1 interferons (IFN-1) are major drivers of disease activity in systemic (SLE) and cutaneous lupus erythematosus (CLE). Plasmacytoid dendritic cells (pDCs) the producers IFN-1 during viral infection. pDCs reduced circulation SLE have recently been shown to an exhausted phenotype, suggesting that pathogenic were located end organs. We performed imaging mass cytometry treatment naïve CLE skin...