Lichen planus is a dermatologic disease of unknown etiology characterized by keratotic plaques on the skin. Many patients also harbor white lesions of the oral mucosa. The literature contains numerous reports of lichen planus-like lesions evolving in conjunction with the administration of a variety of pharmacologic agents. It is difficult, if not impossible, to distinguish such lesions from one...

Lupus erythematosus, especially the discoid form, and lichen planopilaris may be associated and can occur in different topographies (coexistence) or in the same lesion (lupus eythematosus/lichen planus overlap syndrome). Frontal fibrosing alopecia is considered a variant form of lichen Received: October 24, 2016 Accepted: October 27, 2016 Published online: November 12, 2016 Leandro Noriega Derm...

Lichen planus is a fairly distinctive, chronic, immunologically mediated mucocutaneous disease, of uncertain etiology that was first described as a disease of the skin that can also affect mucosal surfaces, including those that line the oral cavity. The prevalence of LP in the general population is of the order of 0.9 to 1.2%. It is stated that approximately 40% of lesions occur on both oral an...

Introduction: Malondialdehyde (MDA) is a useful determinant to show high level of lipid peroxidation which lead to impaired cell function. Previous studies have mentioned there is a relationship between high oxidative stress and low anti-oxidant activity in patients with oral lichen planus. The aim of this study was to evaluate serum level of Malondialdehyde as an indicator of oxidative stress ...

Background Lichen sclerosus most commonly affects the genital area. Contrarily to lichen planus, the involvement of the oral or vaginal mucosa is rare. Only four cases of vaginal lichen sclerosus have been described in the literature. Case report The authors report two cases of postmenopausal women with a history of vulvar pruritus and burning. Both presented with lesions of the vaginal mucos...

BACKGROUND Lichen planopilaris is a frequent presentation of primary cicatricial alopecia. Scalp distribution characterizes the main clinical presentations: classic lichen planopilaris, frontal fibrosing alopecia and Graham-Little Piccardi-Lassueur Syndrome (GLPLS). OBJECTIVE Description of the clinical, dermoscopic and histopathological findings of Lichen planopilaris in public and private p...

The purpose of this study was to determine the prevalence of oral lichen planus in a population of patients with diabetes mellitus compared with a control population and to determine if patient medications had any influence on the presence of such lesions. Two hundred seventy-three patients with diabetes and an identical number of age-, gender- and race-matched controls were examined for clinic...

Lichen studies, including biodiversity, phylogenetic relationships, and conservation concerns require definitive species identification, however many lichens can be challenging to identify at the species level. Molecular techniques have shown efficacy in discriminating among lichen taxa, however, obtaining genomic DNA from herbarium and fresh lichen thalli by conventional methods has been diffi...

In several families, multiple endocrine neoplasia type 2A (MEN 2A) has been found in association with cutaneous lichen amyloidosis. It has been debated, however, whether the skin amyloidosis found in MEN 2A families, localized exclusively in the interscapular area, represents the same anomaly as that found in autosomal dominant familial cutaneous lichen amyloidosis, which is more generalized. W...

background: proliferating cell nuclear antigen (pcna) is a nuclear protein synthesized in the late g1 and s-phase of the cell cycle. detection of this protein represents a useful marker of the proliferation status of lesions. this study has been carried out to evaluate the cell proliferation rate in oral lichen planus (olp) and comparison between plaque and erosive lichen planus, which indicate...