OBJECTIVE To assess the diagnostic performance of serum CA-125 measurement in the detection of endometriosis. DESIGN Meta-analysis. SETTING AND PATIENT(S) Twenty-three studies comparing serum CA-125 levels and laparoscopically confirmed endometriosis. INTERVENTION(S) Serum CA-125 measurement and laparoscopy. MAIN OUTCOME MEASURE(S) Sensitivity and specificity of serum CA-125 measurement...

PURPOSE Mycobacterium tuberculosis is endemic in Korea. Because tuberculous peritonitis is characterized by ascites, abdominal pain, abdominal mass and elevation of serum CA-125, it can be confused with ovarian malignancies. The aim of this study was to evaluate the significance of serum CA-125 level in the differential diagnosis of tuberculous peritonitis and ovarian malignancy in a Mycobacter...

BACKGROUND Recent studies have proposed the measurement of CA 19-9 and IL-6 as an alternative to CA 125 as markers for endometriosis. This study was performed in order to verify the clinical value of serum CA 125, CA 19-9 and IL-6 levels, either by themselves or combined, in the detection of the disease. METHODS In a prospective cohort study, serum concentrations of CA 125, CA 19-9 and IL-6 w...

Aim: Lung cancer (LC) is a common and mortal malignancy. Tumor biomarkers are measurable biochemicals associated with cells. markers cannot diagnose cancer; instead, they can be used as laboratory tests to support the diagnosis. In this study, we aimed investigate place of tumor in lung histological types. Materials Methods: The study included 121 stage IV patients, 79% whom were male, between ...

BACKGROUND The CA-125 tumor marker has limitations when used to distinguish between benign and malignant ovarian masses. We therefore establish likelihood curves of six subgroups of ovarian pathology based on CA-125 and menopausal status. METHODS This cross-sectional study conducted by the International Ovarian Tumor Analysis group involved 3,511 patients presenting with a persistent adnexal ...

We used decision analysis techniques with Markov cohort modeling to examine the role of cancer antigen 125 (CA-125) in follow-up surveillance strategies among patients with advanced ovarian cancer. Utilities were derived from a societal perspective.Using quality-adjusted life years (QALYS) as the outcome variable, the value of CA-125 monitoring for asymptomatic women with ovarian cancer was fou...

CA 125 has been extensively evaluated as a serum marker for monitoring patients with epithelial ovarian carcinoma. Recently, consideration has been given to the use of CA 125 as one component in a strategy for early detection of this disease. A number of benign conditions can, however, increase CA 125 in serum, limiting the utility of a single antigen determination for identifying ovarian cance...

Purpose: Tumor markers can be used to predict the prognostic factors in patients with breast cancer and, in this study, correlation between CA 15-3, CEA, and CA 125 and the prognostic factors in breast cancer is evaluated. Material and Methods: Patients treated for breast cancer between 2002 2004 were prospectively included in the study. Serum levels of CA 15-3, CEA, and CA 125 were evaluated i...

Effective treatment of ovarian cancer depends upon the early detection of the malignancy. Here, we report on the development of a new nanostructured immunosensor for early detection of cancer antigen 125 (CA-125). A gold electrode was modified with mercaptopropionic acid (MPA), and then consecutively conjugated with silica coated gold nanoparticles (AuNP@SiO2), CdSe quantum dots (QDs) and anti-...