نتایج جستجو برای: ژن hbsag

تعداد نتایج: 20716  

Journal: :Hepatology 2011
Yun-Fan Liaw

This clinically relevant review focuses on recent findings concerning hepatitis B surface antigen (HBsAg) quantitation in untreated patients and treated patients with chronic hepatitis B. Recent studies and emerging data have shown that both HBsAg and hepatitis B virus (HBV) DNA levels decline during the natural course of a chronic HBV infection; they are lowest in the inactive phase, which is ...

ژورنال: :فصلنامه پژوهشی خون 0
زهرا علیزاده zahra alizadeh مرکز تحقیقات سازمان انتقال خون ایران زهره شریفی zohreh sharifi استادیار مرکز تحقیقات سازمان انتقال خون ایرانسازمان اصلی تایید شده: سازمان انتقال خون ایران (blood transfusion research center) شهرام سمیعی shahram samiei مربی مرکز تحقیقات سازمان انتقال خون ایرانسازمان اصلی تایید شده: سازمان انتقال خون ایران (blood transfusion research center)

شیوع anti-hbc و anti-hbs در اهداکنندگان hbsag منفی در تهران زهرا علیزاده1، دکتر زهره شریفی2، شهرام سمیعی3 چکیده سابقه و هدف غربالگری سرولوژیک رایج برای ویروس های هپاتیت منتقله از طریق خون، به طور چشمگیری خطر انتقال هپاتیت از راه خون را کاهش داده است. اگر خون تنها از نظر آنتی ژن سطحی ویروس هپاتیت b (hbsag) آزمایش شود، در این صورت هپاتیت b مخفی می تواند منجر به ترخیص واحدهای خون حاوی ویروس به شبک...

Journal: :Infection and immunity 1975
G R Irwin A M Allen W H Bancroft J J Karwacki H L Brown R H Pinkerton M Willhight F H Top

A survey of hepatitis B patients, asymptomatic hepatitis B antigen (HBsAg) carriers, and control subjects was conducted to determine the relationship between antigenemia and antigen excretion in saliva, urine, and stool. Radioimmunoassay was used to detect HBsAg. Specificity-confirmed HBsAg was detected in the saliva of 6 (30%) of 20 antigenemic patients, 1 (5%) of 20 nonantigenemic patients, 1...

Journal: :Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2006
Geraldine Kaminski Adel Alnaqdy Intesar Al-Belushi Jameel Nograles Said H Al-Dhahry

OBJECTIVES The aim of this study was to determine the prevalence of hepatitis B surface antigen (HBsAg), hepatitis B core antibodies (anti-HBc) and hepatitis B virus (HBV) DNA among a selected group of Omani blood donors. MATERIALS AND METHODS Two hundred HBsAg-negative donors were screened for anti-HBc. Those found to be positive were investigated for HBV DNA by polymerase chain reaction. HB...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1977
W T London J S Drew

Patients undergoing treatment at a community-based renal dialysis clinic were monitored monthly for hepatitis B surface antigen (HBsAg) and antibody to HBsAg (anti-HBs). Of 160 patients who began treatment HBsAg(-)/anti-HBs(-), 77 subsequently became HBsAg(+). Once HBsAg(+), males were more likely to remain HBsAg(+) indefinitely, whereas females were more likely to convert to HBsAg(-) and devel...

Journal: :Antiviral research 2012
Valentina Svicher Valeria Cento Martina Bernassola Maria Neumann-Fraune Formijn Van Hemert Mengjie Chen Romina Salpini Chang Liu Roberta Longo Michela Visca Sara Romano Valeria Micheli Ada Bertoli Caterina Gori Francesca Ceccherini-Silberstein Cesare Sarrecchia Massimo Andreoni Mario Angelico Antonella Ursitti Alberto Spanò Jing Maria Zhang Jens Verheyen Giuseppina Cappiello Carlo Federico Perno

Occult HBV infection (OBI) is a threat for the safety of blood-supply, and has been associated with the onset of HBV-related hepatocellular carcinoma and lymphomagenesis. Nevertheless, genetic markers in HBsAg (particularly in D-genotype, the most common in Europe) significantly associated with OBI in vivo are missing. Thus, the goal of this study is to define: (i) prevalence and clinical profi...

2017
Chao-Wei Hsu Kung-Hao Liang Chih-Lang Lin Tong-Hong Wang Chau-Ting Yeh

BACKGROUND The concentrations of hepatitis B virus (HBV) DNA and surface antigen (HBsAg) are two critical virological variables to be monitored in chronic hepatitis B. HBsAg is derived from the HBV genome. Thus, higher HBV-DNA concentrations should implicate higher HBsAg levels. Nevertheless, the two variables do not manifest a simple linear relationship due to elusive host factor involvements....

2013
Lei Xu Zhen Yu Wen Fan Xueping Wang Mingshui Xie Yiting Xu Lihua Hu Yirong Li

BACKGROUND RF(Rheumatoid factor) is usually thought to cause positive interference in immunoassay. Recently, our study showed that high-concentration RFs caused negative interference as well as positive interference in serum HBsAg(Hepatitis B surface antigen) ELISA(Enzyme-linked immunosorbent assay), but it is unclear that RF causing negative interference is an anomaly produced by a certain ELI...

2017
Cheng-Yuan Peng Hsueh-Chou Lai Wen-Pang Su Chia-Hsin Lin Po-Heng Chuang Sheng-Hung Chen Ching-Hsiang Chen

Early declines in serum hepatitis B surface (HBsAg) levels, their optimal cutoffs, and association with therapeutic endpoints in chronic hepatitis B (CHB) patients receiving entecavir treatment remain unclear. We prospectively enrolled 529 patients (195 hepatitis B e antigen [HBeAg]-positive and 334 HBeAg-negative) with a median treatment duration of 49.2 months. Median HBsAg levels declined si...

Journal: :Annals of hepatology 2014
Sandro C Ferreira Silvana G F Chachá Fernanda F Souza Andreza C Teixeira Rodrigo C Santana Márcia G Villanova Sérgio Zucoloto Leandra N Ramalho Gleici S C Perdoná Afonso D C Passos Ana L C Martinelli

INTRODUCTION Few studies have evaluated the factors involved in the spontaneous HBsAg seroclearance in patients with chronic hepatitis B (HBV) followed up on a long-term basis from areas with a low prevalence of HBV infection. We aimed to determine the rate of spontaneous HBsAg seroclearance and the factors related to it in patients with chronic HBV infection followed up at the Hepatitis Outpat...

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